基于监督机器学习的新型预测模型监测术后游离皮瓣的可靠性。

Reliability of Postoperative Free Flap Monitoring with a Novel Prediction Model Based on Supervised Machine Learning.

机构信息

From the Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College and Chang Gung University.

出版信息

Plast Reconstr Surg. 2023 Nov 1;152(5):943e-952e. doi: 10.1097/PRS.0000000000010307. Epub 2023 Feb 15.

Abstract

BACKGROUND

Postoperative free flap monitoring is a critical part of reconstructive microsurgery. Postoperative clinical assessments rely heavily on specialty-trained staff. Therefore, in regions with limited specialist availability, the feasibility of performing microsurgery is restricted. This study aimed to apply artificial intelligence in postoperative free flap monitoring and validate the ability of machine learning in predicting and differentiating types of postoperative free flap circulation.

METHODS

Postoperative data from 176 patients who received free flap surgery were prospectively collected, including free flap photographs and clinical evaluation measures. Flap circulation outcome variables included normal, arterial insufficiency, and venous insufficiency. The Synthetic Minority Oversampling Technique plus Tomek Links (SMOTE-Tomek) was applied for data balance. Data were divided into 80%:20% for model training and validation. Shapley Additive Explanations were used for prediction interpretations of the model.

RESULTS

Of 805 total included flaps, 555 (69%) were normal, 97 (12%) had arterial insufficiency, and 153 (19%) had venous insufficiency. The most effective prediction model was developed based on random forest, with an accuracy of 98.4%. Temperature and color differences between the flap and the surrounding skin were the most significant contributing factors to predict a vascular compromised flap.

CONCLUSIONS

This study demonstrated the reliability of a machine-learning model in differentiating various types of postoperative flap circulation. This novel technique may reduce the burden of free flap monitoring and encourage the broader use of reconstructive microsurgery in regions with a limited number of staff specialists.

摘要

背景

术后游离皮瓣监测是重建显微手术的关键环节。术后临床评估高度依赖专业训练有素的医护人员。因此,在专家资源有限的地区,显微外科手术的可行性受到限制。本研究旨在将人工智能应用于术后游离皮瓣监测,并验证机器学习在预测和区分术后游离皮瓣循环类型方面的能力。

方法

前瞻性收集了 176 例接受游离皮瓣手术患者的术后数据,包括游离皮瓣照片和临床评估测量值。皮瓣循环结局变量包括正常、动脉供血不足和静脉回流不足。采用 Synthetic Minority Oversampling Technique plus Tomek Links(SMOTE-Tomek)进行数据平衡处理。数据分为 80%:20%用于模型训练和验证。采用 Shapley Additive Explanations 对模型的预测解释进行分析。

结果

在总共纳入的 805 个皮瓣中,555 个(69%)为正常,97 个(12%)存在动脉供血不足,153 个(19%)存在静脉回流不足。基于随机森林建立的预测模型最为有效,准确率为 98.4%。皮瓣与周围皮肤之间的温度和颜色差异是预测血管受损皮瓣的最重要影响因素。

结论

本研究证明了机器学习模型在区分不同类型术后皮瓣循环方面的可靠性。这种新技术可能会减轻游离皮瓣监测的负担,并鼓励在专家资源有限的地区更广泛地应用重建显微外科技术。

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