Tabata M
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan.
Hokkaido Igaku Zasshi. 1987 Jul;62(4):528-36.
During the period from 1977 to 1986, 860 patients with cervical cancer were examined ovarian metastasis in our department. Four hundred and seventy seven patients of stage 0 and Ia were treated by a simple hysterectomy without oophorectomy. Follow-up examinations on these stages revealed no recurrence in the ovaries and 5 year survival rate is 100%(239/239). In 383 patients with invasive carcinoma in stage Ib to stage III, who were treated by radical hysterectomy, histological examinations were performed to detect ovarian metastasis. In invasive cases of epidermoid carcinoma(stage Ib to stage III), no ovarian metastases were detected, despite discovery of metastases to the pelvic lymph node in 22.3% of the cases. Conversely, in the cases of cervical adenocarcinoma(pure adenocarcinoma and mixed carcinoma), 9 of 74 cases(12.2%) showed ovarian metastases even in early histologic stages. It is noteworthy that seven of nine cases had no lymph node metastasis. Only endocervical type had ovarian metastasis in pure adenocarcinoma. In mixed carcinoma, metastatic lesion of ovary is adenocarcinoma.
1977年至1986年期间，我科对860例宫颈癌患者进行了卵巢转移情况检查。477例0期和Ia期患者接受了单纯子宫切除术，未行卵巢切除术。对这些分期的患者进行随访检查，未发现卵巢复发，5年生存率为100%（239/239）。383例Ib期至III期浸润性癌患者接受了根治性子宫切除术，并进行了组织学检查以检测卵巢转移情况。在浸润性表皮样癌（Ib期至III期）病例中，尽管22.3%的病例发现有盆腔淋巴结转移，但未检测到卵巢转移。相反，在宫颈腺癌（纯腺癌和混合癌）病例中，74例中有9例（12.2%）即使在早期组织学阶段也出现了卵巢转移。值得注意的是，9例中有7例没有淋巴结转移。纯腺癌中只有宫颈内膜型有卵巢转移。在混合癌中，卵巢转移灶为腺癌。
