终末期肾病中的衰弱：当前观点。
Frailty in end stage renal disease: Current perspectives.
机构信息
Department of Nephrology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
Department of Medicine, Whakatane Hospital, New Zealand.
出版信息
Nefrologia (Engl Ed). 2022 Sep-Oct;42(5):531-539. doi: 10.1016/j.nefroe.2021.05.008.
Frailty is common in end stage renal disease (ESRD) and is a marker of poor outcomes. Its prevalence increases as chronic kidney disease (CKD) progresses. There are different measurement tools available to assess frailty in ESRD. The pathogenesis of frailty in ESRD is multifactorial including uraemia and dialysis related factors. In this current review, we discuss the importance of frailty, its pathogenesis, screening methods, prognostic implications and management strategies in context of ESRD.
虚弱是终末期肾病（ESRD）的常见症状，也是预后不良的标志。随着慢性肾脏病（CKD）的进展，其患病率会增加。有不同的测量工具可用于评估 ESRD 中的虚弱程度。ESRD 中虚弱的发病机制是多因素的，包括尿毒症和与透析相关的因素。在本综述中，我们讨论了虚弱在 ESRD 中的重要性、发病机制、筛查方法、预后意义和管理策略。
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