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老年慢性肾脏病患者的衰弱

Frailty in elderly people with chronic kidney disease.

作者信息

Portilla Franco Maria Eugenia, Tornero Molina Fernando, Gil Gregorio Pedro

机构信息

Servicio de Geriatría, Hospital Clínico San Carlos, Madrid, España.

Servicio de Nefrología, Hospital Clínico San Carlos, Madrid, España.

出版信息

Nefrologia. 2016 Nov-Dec;36(6):609-615. doi: 10.1016/j.nefro.2016.03.020. Epub 2016 May 27.

Abstract

In recent years, the concept of frailty as a "state of pre-disability" has been widely accepted by those involved in the care of the elderly. Its importance lies not only in its high prevalence - more than 25% in people over 85 years of age - but it is also considered an independent risk factor of disability, institutionalisation and mortality amongst the elderly. The study of renal function is relevant in patients with major comorbidities. Studies have shown a significant association between chronic kidney disease and the development of adverse clinical outcomes such as heart disease, heart failure, end-stage renal disease, increased susceptibility to infections and greater functional impairment. Frailty can be reversed, which is why a study of frailty in patients with chronic kidney disease is of particular interest. This article aims to describe the association between ageing, frailty and chronic kidney disease in light of the most recent and relevant scientific publications.

摘要

近年来,衰弱作为一种“残疾前状态”的概念已被从事老年护理工作的人员广泛接受。其重要性不仅在于其高患病率——85岁以上人群中超过25%——而且它还被认为是老年人残疾、入住养老院和死亡的独立危险因素。对合并有主要疾病的患者进行肾功能研究具有重要意义。研究表明,慢性肾脏病与不良临床结局的发生显著相关,如心脏病、心力衰竭、终末期肾病、感染易感性增加和功能障碍加重。衰弱是可以逆转的,这就是为什么对慢性肾脏病患者的衰弱进行研究特别有意义。本文旨在根据最新的相关科学出版物描述衰老、衰弱和慢性肾脏病之间的关联。

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