Department of GI Surgery, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, 700020, West Bengal, India.
Department of GI Surgery, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research, 244 A. J. C. Bose Road, Kolkata, 700020, West Bengal, India.
Am J Surg. 2023 Jul;226(1):93-98. doi: 10.1016/j.amjsurg.2023.02.004. Epub 2023 Feb 7.
The purpose of this study is to review our experience in patients who underwent re-operation for delayed biliary complications after choledochal cyst (CDC) excision.
All the patients who underwent re-operation. for delayed biliary complications after CDC excision between August 2007 and July 2020 were included in this retrospective study. The outcomes of these patients were compared with those who underwent primary surgery (CDC excision) at our institution.
Of the total 40 patients with delayed biliary complications, 25 (62.5%) were female. Thirty-seven (92.5%) patients had a history of cholangitis. The median interval between CDC excision and the reoperation was 70 (4-216) months. The median duration of symptoms before reoperation was 12 (2.5-84) months. Re-do hepaticojejunostomy and direct hepaticojejunostomy were performed in 34 and in 6 patients respectively. Median operative time and blood losses were 219 min and 150 ml respectively. The median postoperative stay was 9 days. Postoperative complications developed in 10 (25%) patients. There was no operative mortality. Over a median follow-up of 71 months, a satisfactory outcome was achieved in 86% of patients. Restricture and intrahepatic stones developed in three and two patients respectively. Incidence of type IV cyst, cholangitis before operation, and operative blood loss were significantly more in the re-operative group. Clinical outcomes like the incidence of recurrent cholangitis, re-stricture, and postoperative hospital stay were comparable between the two groups.
Surgery affords excellent results for majority of the patients with delayed biliary complications after CDC excision. Type IV cysts are more commonly associated with the development of delayed biliary complications.
本研究旨在回顾我们在因先天性胆总管囊肿(CDC)切除术后发生迟发性胆道并发症而接受再次手术的患者中的经验。
本回顾性研究纳入了 2007 年 8 月至 2020 年 7 月期间因 CDC 切除术后迟发性胆道并发症而接受再次手术的所有患者。将这些患者的结果与在我院接受初次手术(CDC 切除术)的患者进行比较。
在总计 40 例迟发性胆道并发症患者中,女性 25 例(62.5%)。37 例(92.5%)患者有胆管炎病史。CDC 切除术后与再次手术之间的中位间隔时间为 70(4-216)个月。再次手术前症状的中位持续时间为 12(2.5-84)个月。再次行肝肠吻合术和直接肝肠吻合术的患者分别为 34 例和 6 例。中位手术时间和出血量分别为 219 分钟和 150 毫升。中位术后住院时间为 9 天。10 例(25%)患者发生术后并发症。无手术死亡。中位随访 71 个月后,86%的患者获得满意的结果。3 例患者发生再狭窄,2 例患者发生肝内结石。再次手术组的 IV 型囊肿、术前胆管炎和手术出血量明显更多。两组患者的复发性胆管炎、再狭窄和术后住院时间等临床结果相似。
对于因先天性胆总管囊肿切除术后发生迟发性胆道并发症的大多数患者,手术可获得良好的结果。IV 型囊肿更常与迟发性胆道并发症的发生相关。