计划接受放疗的头颈癌患者进行预防性口腔护理所需时间：一项单中心前瞻性队列研究。

Time required for prophylactic oral care in head and neck cancer patients scheduled for radiotherapy: A single center, prospective cohort study.

作者信息

Bhandari Sudhir, Wadhwa Soni Bhavita, Gupta Ankita, Ghoshal Sushmita

机构信息

Unit of Prosthodontics, Oral Health Sciences Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Radiation Oncology, Advanced Centre for Treatment, Research, and Education in Cancer, Tata Memorial Centre, HBNI, Navi Mumbai, India.

出版信息

Head Neck. 2023 Apr;45(4):913-920. doi: 10.1002/hed.27317. Epub 2023 Feb 16.

DOI:10.1002/hed.27317

PMID:36794635

Abstract

BACKGROUND

Prophylactic oral care (POC) before radiotherapy (RT) is an adjunct but an integral process toward preparing patients for RT, however, time to be invested in POC remains unexplored.

METHODS

Prospective treatment records were maintained in head and neck cancer patients, who received POC following a standardized protocol with definite timelines. Data collected for oral treatment time (OTT), interruption in RT due to oro-dental issues, future extraction(s), and incidence of osteoradionecrosis (ORN) up to 18 months after treatment were analyzed.

RESULTS

Three hundred thirty-three patients, 275 males and 58 females, mean age 52.45 ± 11.2 years were included. Mean OTT was 21.0 ± 6.2 days and was influenced significantly with the number of extractions (p < 0.00). There was no interruption in RT schedule due to oro-dental issues. Five patients were diagnosed with ORN.

CONCLUSION

Performing POC as demonstrated aid in timely removal of nidus of infection(s), perform RT as scheduled, and maintain satisfactory oral health through the survivorship of patients.

摘要