The Eye Institute of West Florida, Largo, FL.
Cornea. 2024 Jan 1;43(1):26-30. doi: 10.1097/ICO.0000000000003255. Epub 2023 Feb 15.
The objective of this study was to evaluate the clinical outcomes of the TissueTuck technique in the treatment of eyes with recurrent pterygium.
A retrospective review was performed on patients with recurrent pterygium who underwent surgical excision, followed by the application of cryopreserved amniotic membrane, using the TissueTuck technique between January 2012 and May 2019. Only patients with at least 3 months of follow-up were included for analysis. Baseline characteristics, operative time, best-corrected visual acuity, and complications were assessed.
A total of 44 eyes of 42 patients (age 60.5 ± 10.9 yrs) with single-headed (84.1%) or double-headed (15.9%) recurrent pterygium were included for analysis. The average surgical duration was 22.4 ± 8.0 minutes, and mitomycin C was administered intraoperatively in 31 eyes (72.1%). During a mean postoperative follow-up of 24.6 ± 18.3 months, there was only 1 case of recurrence (2.3%). Other complications include scarring (9.1%), granuloma formation (20.5%), and corneal melt in 1 patient with preexisting ectasia (2.3%). Best-corrected visual acuity significantly improved from 0.16 Logarithm of the Minimum Angle of Resolution at baseline to 0.10 Logarithm of the Minimum Angle of Resolution at the last postoperative follow-up ( P = 0.014).
TissueTuck surgery with cryopreserved amniotic membrane is safe and effective for recurrent pterygium cases with a low risk of recurrence and complications.
本研究旨在评估 TissueTuck 技术在治疗复发性翼状胬肉中的临床疗效。
对 2012 年 1 月至 2019 年 5 月期间采用手术切除联合冷冻羊膜移植,应用 TissueTuck 技术治疗的复发性翼状胬肉患者进行回顾性分析。仅纳入随访时间至少 3 个月的患者进行分析。评估患者的基本特征、手术时间、最佳矫正视力和并发症。
共纳入 42 例(60.5±10.9 岁)44 只眼的单头(84.1%)或双头(15.9%)复发性翼状胬肉患者。平均手术时间为 22.4±8.0 分钟,31 只眼(72.1%)术中应用丝裂霉素 C。平均随访 24.6±18.3 个月后,仅 1 例(2.3%)复发。其他并发症包括瘢痕形成(9.1%)、肉芽肿形成(20.5%)和 1 例伴角膜扩张的患者发生角膜溶解(2.3%)。最佳矫正视力由基线时的 0.16 对数最小角分辨率显著提高至末次随访时的 0.10 对数最小角分辨率(P=0.014)。
应用冷冻羊膜的 TissueTuck 手术治疗复发性翼状胬肉安全有效,复发率和并发症发生率低。