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乳腺癌晚期乳房切除术缺损的反向腹成形术。

Reverse Abdominoplasty for Mastectomy Defect Closure in Advanced Breast Cancer.

机构信息

From the University of South Florida Morsani College of Medicine.

Moffitt Cancer Center, Tampa, FL.

出版信息

Ann Plast Surg. 2023 Mar 1;90(3):204-208. doi: 10.1097/SAP.0000000000003439.

DOI:10.1097/SAP.0000000000003439
PMID:36796040
Abstract

BACKGROUND

Breast cancer patients with locally advanced breast cancer who require radical mastectomy are left with large chest wall defects. This poses a significant reconstructive challenge as many high-risk patients require timely postmastectomy adjuvant therapy. While the reverse abdominoplasty technique is commonly used for aesthetic improvement of the anterior trunk, it can be also be effectively used for closure of extensive mastectomy defects in this patient population.

METHODS

We conducted a retrospective cohort study of all consecutive patients who underwent an extensive radical mastectomy followed by immediate closure with the reverse abdominoplasty technique at a single tertiary cancer center from June 2017 to July 2022. Patients who had concurrent skin grafting or breast mound flap reconstruction were excluded. Demographic, medical, oncologic, and reconstructive data were collected.

RESULTS

Six patients were treated with reverse abdominoplasty for 9 chest wall defects after surgical excision of locally advanced breast cancer. The median tumor size was 10.7 cm (range, 6.7-10 cm) and the median mastectomy weight was 865.7 g (range, 356.4-1247.7 g). On average, the operation length was 191 minutes (range, 86-257 minutes) and the postoperative length of stay was 2.2 days (range, 1-5 days). All patients underwent systemic adjuvant therapy and the median time from surgery to initiation of therapy was 44.5 days (range, 32-75 days).

CONCLUSIONS

Reverse abdominoplasty is a simple and safe technique to reliably close large defects after locally advanced breast cancer excision. It has a short operative time, hospital stay, and turnaround time to initiation of adjuvant therapy.

摘要

背景

局部晚期乳腺癌患者需要根治性乳房切除术,术后会遗留大面积胸壁缺损。这给重建带来了巨大的挑战,因为许多高危患者需要及时进行辅助治疗。虽然反向腹成形术通常用于改善前躯的美观,但在这类患者群体中,它也可以有效地用于广泛乳房切除术后缺损的闭合。

方法

我们对 2017 年 6 月至 2022 年 7 月期间在一家三级癌症中心接受广泛根治性乳房切除术并立即采用反向腹成形术进行即刻闭合的所有连续患者进行了回顾性队列研究。排除同期行皮肤移植或乳房隆乳瓣重建的患者。收集了人口统计学、医学、肿瘤学和重建数据。

结果

6 例患者接受了反向腹成形术,用于 9 例局部晚期乳腺癌切除术后的胸壁缺损。肿瘤大小中位数为 10.7cm(范围,6.7-10cm),乳房切除术重量中位数为 865.7g(范围,356.4-1247.7g)。平均手术时间为 191 分钟(范围,86-257 分钟),术后住院时间为 2.2 天(范围,1-5 天)。所有患者均接受了系统辅助治疗,从手术到开始治疗的中位时间为 44.5 天(范围,32-75 天)。

结论

反向腹成形术是一种简单而安全的技术,可可靠地闭合局部晚期乳腺癌切除术后的大面积缺损。它具有较短的手术时间、住院时间和辅助治疗开始时间。

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