University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
J Diabetes. 2023 Feb;15(2):190-195. doi: 10.1111/1753-0407.13363.
This study demonstrates that initiation of glucagon‐like peptide‐1 receptor agonists among individuals with type 2 diabetes (T2D), including those with concomitant atherosclerotic cardiovascular disease (ASCVD), has remained low in the United States between 2014 and 2019, despite clinical evidence supporting their use for cardiovascular risk reduction. These findings add to the existing literature to highlight a gap in adherence to current practice guidelines, which suggests that most patients with T2D and ASCVD in the United States may not be receiving optimal risk‐reducing therapies.
这项研究表明,尽管有临床证据支持使用胰高血糖素样肽-1 受体激动剂(GLP-1RA)来降低心血管风险,但在美国,2014 年至 2019 年间,2 型糖尿病(T2D)患者(包括合并动脉粥样硬化性心血管疾病(ASCVD)的患者)开始使用 GLP-1RA 的比例仍然很低。这些发现增加了现有文献的内容,突出了对当前实践指南的遵从性存在差距,这表明美国大多数患有 T2D 和 ASCVD 的患者可能并未接受最佳的降低风险治疗。