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选择性冻卵:ART 现状。

Elective egg freezing: State of the ART.

机构信息

MBBS(Adel), FRANZCOG, MClinEpid, MReproMed, MHealth@MedLaw, MBioeth, GradCertEBM, Associate Professor, Faculty of Medicine and Health Sciences, University of Melbourne, Melbourne, Vic; Consultant, Reproductive Biology Unit, The Royal Women@s Hospital, Melbourne, Vic; Clinical Director, Melbourne IVF, East@Melbourne, Vic.

BMedSci, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW.

出版信息

Aust J Gen Pract. 2023 Jan-Feb;52(1-2):20-23. doi: 10.31128/AJGP-08-22-6546.

Abstract

BACKGROUND

Women are having children later in life, and the risk and prevalence of involuntary childlessness is thus increasing. Oocyte storage is widely available and increasingly used for elective (non-medical) indications by women trying to safeguard future fertility. There is controversy, however, regarding who should consider oocyte freezing, at what age and how many oocytes should be frozen.

OBJECTIVE

The aim of this article is to provide an update on the practical management of non-medical oocyte freezing, including patient counselling and selection.

DISCUSSION

The latest studies indicate that younger women are less likely to return to use their frozen oocytes, while a live birth is far less likely to result from oocytes frozen at an older age. While not guaranteeing a future pregnancy, oocyte cryopreservation is also associated with a substantial financial burden and uncommon but serious complications. Therefore, patient selection, appropriate counselling and maintenance of realistic expectations are crucial for this new technology to be used with the greatest positive impact.

摘要

背景

女性生育年龄较晚,因此非意愿性不孕的风险和发生率正在增加。卵子冷冻技术广泛应用于女性的选择性(非医学)生育力保存,越来越多的女性选择该技术。然而,关于谁应该考虑卵子冷冻、在什么年龄以及冷冻多少个卵子,存在争议。

目的

本文旨在介绍非医学性卵子冷冻的实用管理方法,包括患者咨询和选择。

讨论

最新研究表明,年轻女性更不可能回院使用冷冻的卵子,而年龄较大时冷冻的卵子,活产的可能性更低。尽管卵子冷冻并不能保证未来妊娠,但也会带来巨大的经济负担和罕见但严重的并发症。因此,对于这项新技术的应用,患者选择、适当的咨询和保持现实的期望至关重要,以最大限度地发挥其积极影响。

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