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《长江三角洲地区女性青少年人乳头瘤病毒疫苗免疫策略与实践专家共识》

[Expert consensus on the immunization strategy and practice of human papillomavirus vaccine for female adolescents in the Yangtze River Delta region].

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Feb 6;57(2):135-153. doi: 10.3760/cma.j.cn112150-20221110-01093.

Abstract

Persistent infection of high-risk human papillomavirus (HPV) is the leading cause of cervical cancer. In order to achieve the goal of cervical cancer elimination, the World Health Organization (WHO) proposed the "90-70-90" goal, one of which is "90% of girls fully vaccinated with HPV vaccine by age 15 years". Based on the epidemiological characteristics of HPV infection and the characteristics of HPV vaccine, it is important to give priority to female adolescents to be vaccinated with HPV vaccine. CAV Affiliated Association for Standardized Management and Practice of Immunization Program organized an expert group to develop an expert consensus on the immunization strategy and practice of human papillomavirus vaccine for female adolescents in the Yangtze River Delta region. This consensus introduces HPV infection and related disease burden, safety, efficacy and effectiveness of HPV vaccination for female adolescents, factors affecting the health benefits of HPV vaccination for female adolescents, current HPV vaccination strategies for female adolescents, the expert advice, common problems and precautions in the Yangtze River Delta region. This consensus is developed to guide HPV vaccination for female adolescents in the Yangtze River Delta region and provide reference for other regions.

摘要

高危型人乳头瘤病毒(HPV)的持续感染是宫颈癌的主要病因。为实现消除宫颈癌的目标,世界卫生组织(WHO)提出了“90-70-90”目标,其中之一是“90%的女孩在15岁前完成HPV疫苗全程接种”。基于HPV感染的流行病学特征和HPV疫苗的特性,优先为女性青少年接种HPV疫苗具有重要意义。中国疫苗行业协会标准化管理与实践附属协会组织专家团队制定了《长江三角洲地区女性青少年人乳头瘤病毒疫苗免疫策略与实践专家共识》。本共识介绍了HPV感染及相关疾病负担、女性青少年HPV疫苗接种的安全性、有效性和效果、影响女性青少年HPV疫苗接种健康效益的因素、当前女性青少年HPV疫苗接种策略、长江三角洲地区的专家建议、常见问题及注意事项。制定本共识旨在指导长江三角洲地区女性青少年HPV疫苗接种工作,并为其他地区提供参考。

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