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Normal Ranges of Thiopurine Methyltransferase Activity Do Not Affect Thioguanine Nucleotide Concentrations With Azathioprine Therapy in Inflammatory Bowel Disease.硫嘌呤甲基转移酶活性的正常范围不影响炎症性肠病患者接受硫唑嘌呤治疗时的硫鸟嘌呤核苷酸浓度。
Crohns Colitis 360. 2020 Jul 11;2(3):otaa058. doi: 10.1093/crocol/otaa058. eCollection 2020 Jul.
2
Quality improvement in healthcare for patients with inflammatory bowel disease.炎症性肠病患者医疗保健的质量改进。
Transl Pediatr. 2019 Jan;8(1):77-82. doi: 10.21037/tp.2019.01.02.
3
Measurements of 6-thioguanine nucleotide levels with TPMT and NUDT15 genotyping in patients with Crohn's disease.检测克罗恩病患者中 TPMT 和 NUDT15 基因分型的 6-硫代鸟嘌呤核苷酸水平。
PLoS One. 2017 Dec 5;12(12):e0188925. doi: 10.1371/journal.pone.0188925. eCollection 2017.
4
Indicators of Quality of Care in Inflammatory Bowel Disease: Seeking the Right Path for Patients.炎症性肠病的医疗质量指标:为患者探寻正确之路
Inflamm Bowel Dis. 2017 May;23(5):702-703. doi: 10.1097/MIB.0000000000001069.
5
Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease.英夫利昔单抗治疗儿童炎症性肠病并不增加恶性肿瘤或噬血细胞性淋巴组织细胞增生症的发生风险。
Gastroenterology. 2017 Jun;152(8):1901-1914.e3. doi: 10.1053/j.gastro.2017.02.004. Epub 2017 Feb 11.
6
Use of thiopurines in inflammatory bowel disease: Safety issues.硫唑嘌呤类药物在炎症性肠病中的应用:安全性问题。
World J Gastrointest Pharmacol Ther. 2014 May 6;5(2):63-76. doi: 10.4292/wjgpt.v5.i2.63.
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Thiopurine monitoring in children with inflammatory bowel disease: a systematic review.炎症性肠病患儿的硫嘌呤监测:一项系统评价
Br J Clin Pharmacol. 2014 Sep;78(3):467-76. doi: 10.1111/bcp.12365.
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Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis.硫唑嘌呤和6-巯基嘌呤用于维持溃疡性结肠炎的缓解
Cochrane Database Syst Rev. 2012 Sep 12(9):CD000478. doi: 10.1002/14651858.CD000478.pub3.
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Relapse rate following azathioprine withdrawal in maintaining remission for Crohn's disease: a meta-analysis.硫唑嘌呤撤药维持克罗恩病缓解后复发率的荟萃分析。
Dig Dis Sci. 2011 Jul;56(7):1929-36. doi: 10.1007/s10620-011-1671-5. Epub 2011 Apr 8.
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Tumor necrosis factor alpha blockers and malignancy in children: forty-eight cases reported to the Food and Drug Administration.肿瘤坏死因子α阻滞剂与儿童恶性肿瘤:向美国食品药品监督管理局报告的48例病例
Arthritis Rheum. 2010 Aug;62(8):2517-24. doi: 10.1002/art.27511.

Thiopurine Methyltransferase Activity and Thiopurine Metabolites in Inflammatory Bowel Disease.

作者信息

El-Matary Wael

机构信息

Section of Pediatric Gastroenterology, Department of Pediatrics, Max Rady College of Medicine, Rady Faculty of Health Sciences and Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Crohns Colitis 360. 2020 Jul 27;2(3):otaa062. doi: 10.1093/crocol/otaa062. eCollection 2020 Jul.

DOI:10.1093/crocol/otaa062
PMID:36798512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9927816/
Abstract
摘要