Pavithra A S, Maiti Subhabrata, Rajeshkumar S, Jessy P
Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
J Adv Pharm Technol Res. 2022 Dec;13(Suppl 2):S416-S420. doi: 10.4103/japtr.japtr_329_22. Epub 2022 Dec 30.
A cast post is a one-piece unit that is custom fabricated for the tooth at the dental laboratory. Traditional extracts such as neem and green tea have good antimicrobial and antioxidant activity against pathogens. The empty canal space may provide a suitable environment for promoting bacterial growth. The main aim of the study is to find the antimicrobial activity of the cast post coated with the nanoparticle. Prepared cast post was coated with prepared green tea and neem-mediated zinc oxide (ZnO) nanoparticles. Culture is done in agar media where control is noncoated post and another is nanoparticle coated post was implanted in the agar media. The zone of inhibition was noted and statistical analysis was done. The maximum zone of inhibition found on (19.333 2.081) followed by (14.000 3.605), and (12.666 2.516). Green tea and neem-mediated ZnO nanoparticle showed good antimicrobial activity against the tester microorganism. Cast post coated with nanoparticles has been proved to be important as it is helpful in the prevention of origin and spread of infection around the canal and through the apical foramen.
铸造桩是在牙科实验室为牙齿定制制作的一体式部件。传统提取物如印楝和绿茶对病原体具有良好的抗菌和抗氧化活性。根管的空隙可能为促进细菌生长提供适宜的环境。该研究的主要目的是探究涂覆有纳米颗粒的铸造桩的抗菌活性。制备的铸造桩涂覆有制备好的绿茶和印楝介导的氧化锌（ZnO）纳米颗粒。在琼脂培养基中进行培养，对照组为未涂覆的桩，另一组是将涂覆有纳米颗粒的桩植入琼脂培养基中。记录抑菌圈并进行统计分析。发现最大抑菌圈为（19.333±2.081），其次是（14.000±3.605）和（12.666±2.516）。绿茶和印楝介导的ZnO纳米颗粒对受试微生物显示出良好的抗菌活性。已证明涂覆有纳米颗粒的铸造桩很重要，因为它有助于预防根管周围及通过根尖孔的感染源和感染传播。
