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卡巴萨拉苦地那姆的抗糖尿病活性。

Antidiabetic activity of Kabasura Kudineer Chooranam.

作者信息

Harini P, Veeraraghavan Vishnu Priya, Selvaraj J, Gayathri R, Kavitha S

机构信息

Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

出版信息

J Adv Pharm Technol Res. 2022 Dec;13(Suppl 2):S383-S386. doi: 10.4103/japtr.japtr_423_22. Epub 2022 Dec 30.

DOI:10.4103/japtr.japtr_423_22
PMID:36798575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9926613/
Abstract

One of the traditional plants used in Siddha medicine is Kabasura Kudineer Chooranam. It is said to possess antiaging, life-strengthening, and disease-preventing activities that have an enormous influence on health care. It has significant therapeutic potential and ethnobotanical significance. The aim of this study is to investigate the antidiabetic activity of Kabasura Kudineer Chooranam. The antidiabetic potential of Kabasura Kudineer Chooranam was determined using established methods such as alpha-amylase and alpha-glucosidase activity. We used one-way ANOVA to see the statistical difference among the groups. The significance thresholds were considered at the < 0.05 level. In comparison with the healthy group, the extract showed a significant antidiabetic effect. The proportion of inhibition increased as the concentrations increased. Previous studies established the antiviral, anti-inflammatory, analgesic, antifungal, antioxidant, antibacterial, hepatoprotective, antiasthmatic, immunomodulatory, and antipyretic effects of Kabasura Kudineer or Choornam. The current findings demonstrated that the Chooranam has good antidiabetic action at a significant concentration. Plant-based products have recently proven to be effective and economical antidiabetic items.

摘要

悉达医学中使用的传统植物之一是卡巴萨拉苦地那尔丸剂。据说它具有抗衰老、增强生命力和预防疾病的活性,对医疗保健有巨大影响。它具有显著的治疗潜力和民族植物学意义。本研究的目的是调查卡巴萨拉苦地那尔丸剂的抗糖尿病活性。采用α-淀粉酶和α-葡萄糖苷酶活性等既定方法测定了卡巴萨拉苦地那尔丸剂的抗糖尿病潜力。我们使用单因素方差分析来观察各组之间的统计学差异。显著性阈值设定在<0.05水平。与健康组相比,提取物显示出显著的抗糖尿病作用。抑制比例随浓度增加而增加。先前的研究证实了卡巴萨拉苦地那尔或丸剂的抗病毒、抗炎、镇痛、抗真菌、抗氧化、抗菌、保肝、抗哮喘、免疫调节和解热作用。目前的研究结果表明,丸剂在有效浓度下具有良好的抗糖尿病作用。最近已证明植物性产品是有效且经济的抗糖尿病物品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ce/9926613/49787aa9925e/JAPTR-13-383-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ce/9926613/ce169883da43/JAPTR-13-383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ce/9926613/49787aa9925e/JAPTR-13-383-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ce/9926613/ce169883da43/JAPTR-13-383-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3ce/9926613/49787aa9925e/JAPTR-13-383-g002.jpg

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Rev Diabet Stud. 2022 Jun 30;18(2):93-99. doi: 10.1900/RDS.2022.18.93.
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Bioinorg Chem Appl. 2022 Mar 25;2022:8635054. doi: 10.1155/2022/8635054. eCollection 2022.
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Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine - A retrospective cohort study.
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