Hodgin E C, Corstvet R E, Blakewood B W
Louisiana Veterinary Medical Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
J Am Vet Med Assoc. 1987 Sep 15;191(6):697-8.
Disseminated cryptococcosis was diagnosed as the cause of death of a 2-week-old pup. Cryptococcus neoformans was isolated from the dam's vaginal discharge, but not from the dam's milk, blood, feces, or environment. During succeeding months, C neoformans was isolated repeatedly from the dam's vagina, even though vaginitis was not evident. One year after the death of the 2-week-old pup, cryptococci could not be isolated from the dam's vagina, and evidence of cryptococcosis was not detected in pups of the dam's next litter. This case was unusual because cryptococcosis has been reported previously only in dogs 11 months or older and because the source of the pup's infection may have been the dam rather than the environment.
播散性隐球菌病被诊断为一只2周龄幼犬的死因。新型隐球菌是从母犬的阴道分泌物中分离出来的，但在母犬的乳汁、血液、粪便或环境中未分离到。在接下来的几个月里，即使没有明显的阴道炎，新型隐球菌仍多次从母犬阴道中分离出来。在这只2周龄幼犬死亡一年后，母犬阴道中未分离到隐球菌，其下一窝幼犬也未检测到隐球菌病迹象。该病例不同寻常，因为此前报道的隐球菌病仅发生在11个月及以上的犬只身上，而且幼犬感染源可能是母犬而非环境。
