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恒河猴因精神性多饮导致的肾髓质溶质耗竭。

Renal medullary solute depletion resulting from psychogenic polydipsia in a rhesus monkey.

作者信息

Fanton J W, Golden J G, David T D

机构信息

Veterinary Sciences Division, US Air Force School of Aerospace Medicine, Brooks AFB, TX 78235-5301.

出版信息

J Am Vet Med Assoc. 1987 Oct 15;191(8):1011-2.

PMID:3679981
Abstract

A rhesus monkey developed psychogenic polydipsia after a change in feeding regimen was instituted. Hyposthenuria, hyponatremia, hypochloremia, and an abnormal calculated plasma osmolality were found. Water deprivation testing and administration of antidiuretic hormone indicated that renal medullary solute depletion had resulted from the prolonged polyuria. Restricted water consumption resulted in resolution of the electrolyte abnormalities and restored ability to excrete concentrated urine.

摘要

一只恒河猴在喂养方案改变后出现了精神性烦渴。发现了低渗尿、低钠血症、低氯血症以及计算得出的血浆渗透压异常。禁水试验和抗利尿激素给药表明,长时间多尿导致了肾髓质溶质耗竭。限制饮水使电解质异常得到缓解,并恢复了排泄浓缩尿的能力。

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