Yi Zuohuizi, Chen Liao, Zheng Hongmei, Chen Changzheng
Eye Center, Renmin Hospital of Wuhan University, Wuhan, China.
Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China.
Ocul Immunol Inflamm. 2023 Aug;31(6):1283-1285. doi: 10.1080/09273948.2023.2176887. Epub 2023 Feb 17.
With the popularity of coronavirus disease 2019 (COVID-19) vaccination, some rare ocular adverse events have gradually been reported. This report shows a rare case of retinal vasculitis following COVID-19 vaccination.
A 37-year-old male complained of unilateral severe vision loss 13 days after the first dose of an inactivated COVID-19 vaccine. The initial eye examination showed gray-white edema in the macula, and scattered patchy gray-white lesions in the peripheral retina, accompanied by peripheral retinal small vessel occlusion. After glucocorticoid treatment, the gray-white lesions gradually subsided. However, due to the initial severe damage in the fundus, macular and peripheral retinal lesions were significantly atrophied, and the vision recovery was poor.
The ocular adverse event in this report may be related to the inactivated COVID-19 vaccination, however, it is difficult to rule out the accidental rare adverse events after a large number of vaccinations.
随着2019冠状病毒病（COVID-19）疫苗接种的普及，一些罕见的眼部不良事件逐渐被报道。本报告展示了1例COVID-19疫苗接种后发生视网膜血管炎的罕见病例。
一名37岁男性在接种第一剂灭活COVID-19疫苗13天后，出现单侧严重视力丧失。初次眼部检查显示黄斑区灰白色水肿，周边视网膜散在片状灰白色病灶，并伴有周边视网膜小血管闭塞。经糖皮质激素治疗后，灰白色病灶逐渐消退。然而，由于眼底最初损伤严重，黄斑及周边视网膜病灶明显萎缩，视力恢复不佳。
本报告中的眼部不良事件可能与灭活COVID-19疫苗接种有关，然而，在大量接种后难以排除偶发的罕见不良事件。
