Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou Vascular and Oncological Interventional Radiology Department, 75015 Paris, France.
Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou Vascular and Oncological Interventional Radiology Department, 75015 Paris, France; Université Paris Cité, 75006 Paris, France.
Diagn Interv Imaging. 2023 Jun;104(6):292-296. doi: 10.1016/j.diii.2023.01.012. Epub 2023 Feb 16.
The purpose of this study was to assess long-term outcome of prostate artery embolization (PAE) in patients presenting with acute urinary retention related to benign prostatic hyperplasia.
All consecutive patients who underwent PAE for acute urinary retention due to benign prostatic hyperplasia from August 2011 to December 2021 in a single institution were retrospectively included. There were 88 men with a mean age of 72 ± 12 (standard deviation [SD]) years (range: 42-99 years). Patients underwent a first attempt of catheter removal two weeks after PAE. Clinical success was defined as the absence of acute urinary retention recurrence. Correlations between long-term clinical success and patient variables or bilateral PAE were searched for using Spearman correlation test. Catheter-free survival was assessed using Kaplan-Meier analysis.
Successful catheter removal in the month following PAE was performed in 72 (72/88; 82%) patients and 16 (16/88; 18%) patients had immediate recurrence. Clinical success persisted for 58 (58/88; 66%) patients at long-term follow-up (mean follow-up: 19.5 months ± 16.5 [SD]; range: 2-74 months). Recurrence occurred at a mean of 16.2 months ± 12.2 (SD) (range: 1.5-43 months) post-PAE. Overall, 21 (21/88; 24%) patients of the cohort underwent prostatic surgery, at a mean of 10.4 months ± 12.2 (SD) (range: 1.2-42.4 months) from initial PAE. No correlations between patients variables or bilateral PAE and long-term clinical success were identified. Kaplan-Meier analysis showed a three-year catheter free probability of 60%.
PAE is a valuable technique for acute urinary retention related to benign prostatic hyperplasia, with a long-term success rate of 66%. However acute urinary retention relapse affects 15% of patients.
本研究旨在评估前列腺动脉栓塞术（PAE）治疗因良性前列腺增生导致急性尿潴留患者的长期疗效。
回顾性分析 2011 年 8 月至 2021 年 12 月在我院接受 PAE 治疗因良性前列腺增生导致急性尿潴留的连续患者。共有 88 名男性，平均年龄 72 ± 12 岁（标准差 [SD]）（范围：42-99 岁）。PAE 后两周行首次导尿管拔除尝试。无急性尿潴留复发定义为临床成功。使用 Spearman 相关检验寻找长期临床成功与患者变量或双侧 PAE 的相关性。采用 Kaplan-Meier 分析评估无导尿管生存情况。
PAE 后 1 个月成功拔除导尿管 72 例（72/88；82%），16 例（16/88；18%）立即复发。长期随访（平均随访时间：19.5 个月±16.5 [SD]；范围：2-74 个月）时 58 例（58/88；66%）患者临床成功。PAE 后平均 16.2 个月±12.2（SD）（范围：1.5-43 个月）复发。总体而言，该队列中有 21 例（21/88；24%）患者在初始 PAE 后 10.4 个月±12.2（SD）（范围：1.2-42.4 个月）行前列腺手术。未发现患者变量或双侧 PAE 与长期临床成功之间的相关性。Kaplan-Meier 分析显示，3 年无导尿管生存概率为 60%。
PAE 是治疗因良性前列腺增生导致急性尿潴留的一种有价值的技术，长期成功率为 66%。然而，15%的患者会出现急性尿潴留复发。
