Osr1 Is a Critical Regulator of Macrophage Polarization in NASH Progression.
作者信息
Lee Jin, Feng Gen-Sheng
机构信息
Department of Pathology; Department of Molecular Biology; Moores Cancer Center, University of California San Diego, La Jolla, California.
Department of Pathology; Department of Molecular Biology; Moores Cancer Center, University of California San Diego, La Jolla, California.
出版信息
Cell Mol Gastroenterol Hepatol. 2023;15(5):1249-1250. doi: 10.1016/j.jcmgh.2023.01.009. Epub 2023 Feb 15.
Abstract
摘要
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Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model.阻断 Osr1 表达可促进高脂肪饮食诱导的小鼠模型肝脂肪变性和炎症。
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