RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase-associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas.
作者信息
Lee Jae W, Hruban Ralph H, Brosens Lodewijk A A, Condello Vincenzo, Nikiforova Marina N, Singhi Aatur D
机构信息
Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Gastroenterology. 2023 Jun;164(7):1310-1313.e6. doi: 10.1053/j.gastro.2023.02.006. Epub 2023 Feb 17.
Abstract
摘要
相似文献
1
RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase-associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas.RNA测序鉴定胰腺导管内乳头状肿瘤中频繁出现的丝裂原活化蛋白激酶相关融合基因。
Gastroenterology. 2023 Jun;164(7):1310-1313.e6. doi: 10.1053/j.gastro.2023.02.006. Epub 2023 Feb 17.
2
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.胰腺导管内管状乳头状肿瘤在遗传学上有别于导管内乳头状黏液性肿瘤和导管腺癌。
Mod Pathol. 2017 Dec;30(12):1760-1772. doi: 10.1038/modpathol.2017.60. Epub 2017 Aug 4.
3
Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.胰腺导管内管状乳头状肿瘤，有别于胰腺上皮内瘤变和导管内乳头状黏液性肿瘤。
Am J Surg Pathol. 2009 Aug;33(8):1164-72. doi: 10.1097/PAS.0b013e3181a162e5.
4
Intraductal Tubulopapillary Neoplasm of the Pancreas: An Update From a Pathologist's Perspective.胰腺导管内管状乳头状肿瘤：病理学家视角的最新进展
Arch Pathol Lab Med. 2016 Oct;140(10):1068-73. doi: 10.5858/arpa.2016-0207-RA.
5
Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.胰腺内导管管状乳头状肿瘤中的 PIK3CA 体细胞突变和 AKT 的激活。
Am J Surg Pathol. 2011 Dec;35(12):1812-7. doi: 10.1097/PAS.0b013e31822769a0.
6
Case report: Intraductal tubulopapillary neoplasm of the pancreas with unique clear cell phenotype.病例报告：具有独特透明细胞表型的胰腺管内管状乳头状肿瘤。
Diagn Pathol. 2014 Jan 20;9:11. doi: 10.1186/1746-1596-9-11.
7
[Intraductal tubulopapillary neoplasm of the pancreas: a clinicopathologic study of 6 cases].[胰腺导管内管状乳头状肿瘤：6例临床病理研究]
Zhonghua Bing Li Xue Za Zhi. 2013 Apr;42(4):248-51. doi: 10.3760/cma.j.issn.0529-5807.2013.04.008.
8
Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas.涉及双特异性磷酸酶6/丝裂原活化蛋白激酶磷酸酶-3（DUSP6/MKP-3）功能障碍的不同进展途径在胰腺上皮内瘤变和胰腺导管内乳头状黏液性肿瘤中的作用。
Mod Pathol. 2005 Aug;18(8):1034-42. doi: 10.1038/modpathol.3800383.
9
Secretin receptors in normal and diseased human pancreas: marked reduction of receptor binding in ductal neoplasia.正常和患病人类胰腺中的促胰液素受体：导管肿瘤中受体结合显著减少。
Am J Pathol. 2005 Oct;167(4):959-68. doi: 10.1016/S0002-9440(10)61186-8.
10
A Case of Pancreatic Ductal Adenocarcinoma Arising From Atypical Flat Lesions.一例源自非典型扁平病变的胰腺导管腺癌
Pancreas. 2020 Aug;49(7):e60-e61. doi: 10.1097/MPA.0000000000001591.
引用本文的文献
1
Precursor lesions in familial and hereditary pancreatic cancer.家族性和遗传性胰腺癌的前驱病变。
Fam Cancer. 2024 Aug;23(3):267-278. doi: 10.1007/s10689-024-00359-2. Epub 2024 Feb 6.
本文引用的文献
1
RASGRF2 gene fusions identified in a variety of melanocytic lesions with distinct morphological features.在具有不同形态特征的各种黑素细胞病变中鉴定出 RASGRF2 基因融合。
Pigment Cell Melanoma Res. 2021 Nov;34(6):1074-1083. doi: 10.1111/pcmr.13004. Epub 2021 Aug 23.
2
Pancreatic intraductal tubulopapillary neoplasm is genetically distinct from intraductal papillary mucinous neoplasm and ductal adenocarcinoma.胰腺导管内管状乳头状肿瘤在遗传学上有别于导管内乳头状黏液性肿瘤和导管腺癌。
Mod Pathol. 2017 Dec;30(12):1760-1772. doi: 10.1038/modpathol.2017.60. Epub 2017 Aug 4.
3
Intraductal Tubulopapillary Neoplasm of the Pancreas: A Clinicopathologic and Immunohistochemical Analysis of 33 Cases.胰腺导管内管状乳头状肿瘤：33例临床病理及免疫组化分析
Am J Surg Pathol. 2017 Mar;41(3):313-325. doi: 10.1097/PAS.0000000000000782.
4
Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells.异常激活的 AREG-EGFR 信号对于 CRTC1-MAML2 融合阳性的黏液表皮样癌细胞的生长和存活是必需的。
Oncogene. 2014 Jul 17;33(29):3869-77. doi: 10.1038/onc.2013.348. Epub 2013 Aug 26.
5
Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas.胰腺内导管管状乳头状肿瘤中的 PIK3CA 体细胞突变和 AKT 的激活。
Am J Surg Pathol. 2011 Dec;35(12):1812-7. doi: 10.1097/PAS.0b013e31822769a0.
6
A potential case of intraductal tubulopapillary neoplasms of the bile duct.胆管内管状乳头状肿瘤的潜在病例。
Pathol Int. 2010 Sep;60(9):630-5. doi: 10.1111/j.1440-1827.2010.02572.x.
7
Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms.胰腺导管内管状乳头状肿瘤，有别于胰腺上皮内瘤变和导管内乳头状黏液性肿瘤。
Am J Surg Pathol. 2009 Aug;33(8):1164-72. doi: 10.1097/PAS.0b013e3181a162e5.
Zotero 插件