老年恶性肝肿瘤患者肝切除术后焦虑抑郁的研究。
Study on anxiety and depression in elderly patients with malignant liver tumor undergoing hepatectomy.
机构信息
Department of General Surgery, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China.
Department of Internal Medicine, Henan Cancer Hospital, Zhengzhou, 450003, China.
出版信息
Eur J Med Res. 2023 Feb 20;28(1):87. doi: 10.1186/s40001-023-01040-7.
BACKGROUND
Patients with malignant tumors are more likely to have psychological problems due to their worries about their life expectancy. To understand the psychological status of elderly patients with malignant liver tumor undergoing hepatectomy better, the study was designed to investigate the current situation of anxiety and depression in elderly patients with malignant liver tumor undergoing hepatectomy and to analyze its related factors.
METHODS
A total of 126 elderly patients with malignant liver tumor undergoing hepatectomy were selected as the research objects. The anxiety and depression of all subjects were evaluated by HADS (Hosptial Anxiety and Depression Scale). The correlation factors affecting the psychological state of elderly patients with malignant liver tumor undergoing hepatectomy were analyzed by linear regression method.
RESULTS
The HADS-A score of elderly patients with malignant liver tumor undergoing hepatectomy was 8.79 ± 2.56, among which 37 patients were asymptomatic, 60 patients with suspicious symptoms, and 29 patients with definite symptoms. The HADS-D score was 8.40 ± 2.97, among which 61 patients were asymptomatic, 39 patients with suspicious symptoms, and 26 patients with definite symptoms. Multivariate analysis using linear regression method showed that FRAIL score, residence, and complication were significantly associated with anxiety and depression of elderly patients with malignant liver tumor undergoing hepatectomy.
CONCLUSIONS
Anxiety and depression in elderly patients with malignant liver tumor undergoing hepatectomy were obvious. FRAIL score, regional differences, and the complication were the risk factors for anxiety and depression in elderly patients with malignant liver tumor undergoing hepatectomy. Improving frailty, reducing regional differences, and preventing complications is beneficial to alleviate the adverse mood of elderly patients with malignant liver tumor undergoing hepatectomy.
背景
由于对预期寿命的担忧，恶性肿瘤患者更容易出现心理问题。为了更好地了解行肝切除术的老年恶性肝肿瘤患者的心理状况，本研究旨在调查行肝切除术的老年恶性肝肿瘤患者焦虑和抑郁的现状，并分析其相关因素。
方法
选择 126 例行肝切除术的老年恶性肝肿瘤患者作为研究对象。采用 HADS（医院焦虑抑郁量表）对所有患者的焦虑和抑郁情况进行评估。采用线性回归法分析影响老年恶性肝肿瘤患者肝切除术后心理状态的相关因素。
结果
老年恶性肝肿瘤患者行肝切除术的 HADS-A 评分为 8.79±2.56，其中无症状 37 例，可疑症状 60 例，确诊症状 29 例。HADS-D 评分为 8.40±2.97，其中无症状 61 例，可疑症状 39 例，确诊症状 26 例。采用线性回归法的多因素分析显示，FRAIL 评分、居住地和并发症与行肝切除术的老年恶性肝肿瘤患者的焦虑和抑郁显著相关。
结论
行肝切除术的老年恶性肝肿瘤患者存在明显的焦虑和抑郁。FRAIL 评分、地区差异和并发症是老年恶性肝肿瘤患者行肝切除术焦虑和抑郁的危险因素。改善虚弱状况、减少地区差异和预防并发症有利于缓解行肝切除术的老年恶性肝肿瘤患者的不良情绪。
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