Kim Joon Kyung, Hansen Anna, Peard Leslie, Newsome Matthew, Saltzman Amanda F
Department of Urology, University of Kentucky, Lexington, KY.
College of Medicine, University of Kentucky, Lexington, KY.
Urology. 2023 Jul;177:178-180. doi: 10.1016/j.urology.2023.01.034. Epub 2023 Feb 16.
Wilms tumor is the most common pediatric renal mass and occurs in up to 10% of predisposition syndromes. One such syndrome is CLOVES syndrome, an extremely rare disorder within the umbrella of PIK3CA-related overgrowth spectrum disorders. This case presents the management of a bilateral Wilms tumor in a patient with CLOVES syndrome and highlights the many intricacies in caring for complex oncology patients. Particularly highlighted in this case is the delicate line in balancing the risks of treatment-related morbidity against the risks of recurrence in predisposed patients, while still abiding by established treatment guidelines.
肾母细胞瘤是最常见的小儿肾脏肿块，在高达10%的易感综合征中出现。其中一种综合征是CLOVES综合征，它是PIK3CA相关过度生长谱系障碍这一范畴内极其罕见的一种疾病。本病例介绍了一名患有CLOVES综合征患者双侧肾母细胞瘤的治疗情况，并突出了护理复杂肿瘤患者时的诸多复杂之处。本病例特别强调的是，在易患患者中平衡治疗相关并发症风险与复发风险之间的微妙界限，同时仍要遵循既定的治疗指南。
