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BQ.1.1、XBB.1 和 XBB.1.5 对癌症患者二价 mRNA COVID-19 加强针的中和作用。

BQ.1.1, XBB.1, and XBB.1.5 neutralization after bivalent mRNA COVID-19 booster in patients with cancer.

机构信息

Department of Oncology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Academy of Geriatric Oncology, Odense University Hospital, Odense, Denmark.

Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.

出版信息

Cancer Cell. 2023 Apr 10;41(4):649-650. doi: 10.1016/j.ccell.2023.02.003. Epub 2023 Feb 9.

Abstract

Ehmsen et al. evaluate the neutralizing capacity to current SARS-CoV-2 variants in patients with cancer before and after receiving the BNT162b2 bivalent mRNA vaccine booster. Bivalent vaccine provides some protection against BQ.1.1 but fails to protect against XBB.1 and XBB.1.5 in patients with cancer.

摘要

埃姆森等人评估了癌症患者在接种 BNT162b2 二价 mRNA 疫苗加强针前后对当前 SARS-CoV-2 变体的中和能力。二价疫苗对 BQ.1.1 提供了一定程度的保护,但不能预防癌症患者感染 XBB.1 和 XBB.1.5。

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