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评估斑秃女性健康相关生活质量的测量工具的信度和效度。

Reliability and validity of a measure to assess the health-related quality of life of women with alopecia areata.

机构信息

Sinclair Dermatology, Melbourne, VIC, Australia.

National and International Skin Registry Solutions (NISR), Dublin, Ireland.

出版信息

Clin Exp Dermatol. 2023 Jun 5;48(6):681-684. doi: 10.1093/ced/llad066.

DOI:10.1093/ced/llad066
PMID:36806573
Abstract

Alopecia areata (AA) has an impact on health-related quality of life (HRQoL). The Women's Androgenetic Alopecia Quality of Life (WAA-QoL) questionnaire is a reliable, validated HRQoL measure in women with androgenetic alopecia (AGA). There is no equivalent measure for female patients with AA. Data were collected as part of the Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS) Australia. The WAA-QoL, Dermatology Life Quality Index (DLQI) and Skindex-16 for AA, as well as the Severity of Alopecia Tool score, were extracted from GRASS for adult female patients. Cronbach's alpha and factor analysis were employed to determine the internal consistency of the measure, and nonparametric correlation testing assessed the validity of the questionnaire. Overall, 137 individuals completed the questionnaires. There was excellent internal consistency of the WAA-QoL among women with AA (Cronbach's α = 0.98). A moderate and high positive correlation was found between the WAA-QoL and the DLQI and the Skindex-16 for AA, respectively. The WAA-QoL is a reliable and valid assessment of HRQoL among women with AA.

摘要

斑秃 (AA) 会影响健康相关生活质量 (HRQoL)。女性雄激素性脱发生活质量 (WAA-QoL) 问卷是评估女性雄激素性脱发 (AGA) 患者 HRQoL 的可靠、有效的工具。目前尚无针对女性 AA 患者的等效评估工具。该数据是作为全球斑秃疾病严重程度和治疗安全性登记处 (GRASS) 澳大利亚部分的一部分收集的。从 GRASS 中提取了 AA 的 WAA-QoL、皮肤病生活质量指数 (DLQI) 和 Skindex-16,以及脱发严重程度工具评分,用于评估成年女性患者。采用克朗巴赫 α 和因子分析来确定该评估工具的内部一致性,非参数相关测试评估问卷的有效性。总体而言,有 137 人完成了问卷调查。AA 女性的 WAA-QoL 具有极好的内部一致性 (克朗巴赫 α = 0.98)。WAA-QoL 与 DLQI 和 AA 的 Skindex-16 之间存在中度至高度的正相关。WAA-QoL 是评估 AA 女性 HRQoL 的可靠和有效的工具。

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引用本文的文献

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Alopecia Areata: Impact on Patients' Quality of Life and Disease Perception: A Survey-Based Study.斑秃:对患者生活质量和疾病认知的影响:一项基于调查的研究
Acta Derm Venereol. 2025 Jul 19;105:adv43318. doi: 10.2340/actadv.v105.43318.
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Psychosocial and mental impact of alopecia areata: Analysis of the Danish Skin Cohort.斑秃的心理社会和精神影响:丹麦皮肤队列分析
J Eur Acad Dermatol Venereol. 2025 Mar;39(3):688-697. doi: 10.1111/jdv.20211. Epub 2024 Jun 28.