From the Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven.
Frank H. Netter School of Medicine, Quinnipiac University, North Haven.
Urogynecology (Phila). 2023 Mar 1;29(3):351-359. doi: 10.1097/SPV.0000000000001267. Epub 2022 Oct 10.
Obstetric anal sphincter injuries (OASIS) predispose for the development of fecal incontinence (FI), but management of subsequent pregnancy after OASIS is controversial.
We aimed to determine if universal urogynecologic consultation (UUC) for pregnant women with prior OASIS is cost-effective.
We performed a cost-effectiveness analysis of pregnant women with a history of OASIS modeling UUC compared with no referral (usual care). We modeled the route of delivery, peripartum complications, and subsequent treatment options for FI. Probabilities and utilities were obtained from published literature. Costs using a third-party payer perspective were gathered from the Medicare physician fee schedule reimbursement data or published literature converted to 2019 U.S. dollars. Cost-effectiveness was determined using incremental cost-effectiveness ratios).
Our model demonstrated that UUC for pregnant patients with prior OASIS was cost-effective. Compared with usual care, the incremental cost-effectiveness ratio for this strategy was $19,858.32 per quality-adjusted life-year, below the willingness to pay a threshold of $50,000/quality-adjusted life-year. Universal urogynecologic consultation reduced the ultimate rate of FI from 25.33% to 22.67% and reduced patients living with untreated FI from 17.36% to 1.49%. Universal urogynecologic consultation increased the use of physical therapy by 14.14%, whereas rates of sacral neuromodulation and sphincteroplasty increased by only 2.48% and 0.58%, respectively. Universal urogynecologic consultation reduced the rate of vaginal delivery from 97.26% to 72.42%, which in turn led to a 1.15% increase in peripartum maternal complications.
Universal urogynecologic consultation in women with a history of OASIS is a cost-effective strategy that decreases the overall incidence of FI, increases treatment utilization for FI, and only marginally increases the risk of maternal morbidity.
产科肛门括约肌损伤(OASIS)易导致粪便失禁(FI)的发生,但 OASIS 后妊娠的管理仍存在争议。
我们旨在确定对有 OASIS 病史的孕妇进行普遍的妇科泌尿学咨询(UUC)是否具有成本效益。
我们对有 OASIS 病史的孕妇进行了 UUC 与不转诊(常规护理)的成本效益分析。我们对分娩方式、围产期并发症以及 FI 的后续治疗方案进行了建模。概率和效用值取自已发表的文献。采用第三方支付者的角度收集成本数据,包括 Medicare 医师费用表报销数据或已发表文献中转换为 2019 年美元的成本数据。使用增量成本效益比来确定成本效益。
我们的模型表明,对有 OASIS 病史的孕妇进行 UUC 具有成本效益。与常规护理相比,该策略的增量成本效益比为每质量调整生命年 19858.32 美元,低于 50000 美元/质量调整生命年的支付意愿阈值。普遍的妇科泌尿学咨询将 FI 的最终发生率从 25.33%降低到 22.67%,并将未经治疗的 FI 患者的比例从 17.36%降低到 1.49%。普遍的妇科泌尿学咨询增加了 14.14%的物理治疗使用率,而骶神经调节和括约肌成形术的使用率仅分别增加了 2.48%和 0.58%。普遍的妇科泌尿学咨询将阴道分娩率从 97.26%降低到 72.42%,这反过来又导致围产期产妇并发症的风险增加了 1.15%。
对有 OASIS 病史的女性进行普遍的妇科泌尿学咨询是一种具有成本效益的策略,可降低 FI 的总体发生率,增加 FI 的治疗利用率,并仅略微增加产妇发病率的风险。