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中国东北地区满族人与朝鲜族人的遗传结构和混合。

The genetic structure and admixture of Manchus and Koreans in northeast China.

机构信息

College of Foreign Languages, Huaqiao University, Quanzhou, China.

State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.

出版信息

Ann Hum Biol. 2023 Feb;50(1):161-171. doi: 10.1080/03014460.2023.2182912.

DOI:10.1080/03014460.2023.2182912
PMID:36809229
Abstract

BACKGROUND

The fine-scale genetic profiles and population history of Manchus and Koreans remain unclear.

AIM

To infer a fine-scale genetic structure and admixture of Manchu and Korean populations.

SUBJECTS AND METHODS

We collected and genotyped 16 Manchus from Liaoning and 18 Koreans from Jilin province with about 700K genome-wide SNPs. We analysed the data using principal component analysis (PCA), ADMIXTURE, Fst, TreeMix, -statistics, , and .

RESULTS

Manchus and Koreans showed a genetic affinity with northern East Asians. Chinese Koreans showed a long-term genetic continuity with Bronze Age populations from the West Liao River and had a strong affinity with Koreans in South Korea and Japan. Manchus had a different genetic profile compared with other Tungusic populations since the Manchus received additional genetic influence from the southern Chinese but didn't have West Eurasian-related admixture.

CONCLUSIONS

The genetic formation of Manchus involving southern Chinese was consistent with the extensive interactions between Manchus and populations from central and southern China. The large-scale genetic continuity between ancient West Liao River farmers and Koreans highlighted the role farming expansion played in the peopling of the Korean Peninsula.

摘要

背景

满人和朝鲜人的精细遗传特征和人口历史仍不清楚。

目的

推断满族和朝鲜人口的精细遗传结构和混合情况。

对象和方法

我们收集并对来自辽宁的 16 名满人和来自吉林的 18 名朝鲜人进行了全基因组约 700K SNPs 的基因分型。我们使用主成分分析(PCA)、ADMIXTURE、Fst、TreeMix、-统计量、来分析数据。

结果

满人和朝鲜人与北亚东亚人具有遗传亲和力。中国朝鲜人与西辽河流域青铜时代的人群有着长期的遗传连续性,与韩国和日本的朝鲜人有着很强的亲和力。与其他通古斯人相比,满人的遗传特征不同,因为满族人受到了来自中国南方的额外遗传影响,但没有与欧亚西部相关的混合。

结论

满族的形成涉及到中国南方,这与满族与中国中部和南部的人口之间的广泛互动是一致的。古代西辽河流域农民与朝鲜人之间的大规模遗传连续性突出了农业扩张在朝鲜半岛人口形成中的作用。

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Ann Hum Biol. 2023 Feb;50(1):161-171. doi: 10.1080/03014460.2023.2182912.
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