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血培养和肌钙蛋白检测在疑似菌血症患者中的应用 - 基于临床检测的风险分层示例。

Blood Culture and Troponin Testing in Suspected Bacteraemic Admissions - Example of Risk Stratification Based on Clinical Testing.

机构信息

MD, Department of Internal Medicine, St James's Hospital, Dublin 8, Ireland.

MD, PhD, Department of Internal Medicine, St James's Hospital, Dublin 8, Ireland.

出版信息

Acute Med. 2022;21(4):176-181. doi: 10.52964/AMJA.0921.

DOI:10.52964/AMJA.0921
PMID:36809448
Abstract

AIM

To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing.

METHODS

We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression.

RESULTS

There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic.

CONCLUSION

Blood culture and hscTnT requests and results predict worse outcomes.

摘要

目的

探讨肌钙蛋白(hscTnT)和血培养检测的临床预测价值。

方法

我们检查了 2011 年至 2020 年期间所有的住院患者。使用多变量逻辑回归评估了基于血培养和 hscTnT 请求/结果的 30 天住院死亡率的预测。使用截断泊松回归分析了住院时间与程序/服务的使用情况之间的关系。

结果

在 42325 例患者中共有 77566 例入院。同时请求血培养和 hscTnT 时,30 天住院死亡率增加至 20.9%(95%CI:19.7,22.1),而仅请求血培养时为 8.9%(95%CI:8.5,9.4),两者均不请求时为 2.3%(95%CI:2.2,2.4)。血培养(95%CI:3.50,4.42)或 hsTnT 请求(95%CI:4.10,5.14)均具有预后意义。

结论

血培养和 hscTnT 请求和结果可预测更差的结局。

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