MD, Department of Internal Medicine, St James's Hospital, Dublin 8, Ireland.
MD, PhD, Department of Internal Medicine, St James's Hospital, Dublin 8, Ireland.
Acute Med. 2022;21(4):176-181. doi: 10.52964/AMJA.0921.
To investigate the clinical predictive value of troponin (hscTnT) and blood culture testing.
We examined all medical admissions from 2011-2020. Prediction of 30-day in-hospital mortality, dependent on blood culture and hscTnT requests/results, was evaluated using multiple variable logistic regression. Length of stay was related to utilization of procedures/services with truncated Poisson regression.
There were 77,566 admissions in 42,325 patients. With both blood cultures and hscTnT requested, 30-day in-hospital mortality increased to 20.9% (95%CI: 19.7, 22.1) vs 8.9% (95%CI: 8.5, 9.4) for blood cultures alone and 2.3% (95%CI: 2.2, 2.4) with neither. Blood culture 3.93 (95%CI: 3.50, 4.42) or hsTnT requests 4.58 (95%CI: 4.10, 5.14) were prognostic.
Blood culture and hscTnT requests and results predict worse outcomes.
探讨肌钙蛋白(hscTnT)和血培养检测的临床预测价值。
我们检查了 2011 年至 2020 年期间所有的住院患者。使用多变量逻辑回归评估了基于血培养和 hscTnT 请求/结果的 30 天住院死亡率的预测。使用截断泊松回归分析了住院时间与程序/服务的使用情况之间的关系。
在 42325 例患者中共有 77566 例入院。同时请求血培养和 hscTnT 时,30 天住院死亡率增加至 20.9%(95%CI:19.7,22.1),而仅请求血培养时为 8.9%(95%CI:8.5,9.4),两者均不请求时为 2.3%(95%CI:2.2,2.4)。血培养(95%CI:3.50,4.42)或 hsTnT 请求(95%CI:4.10,5.14)均具有预后意义。
血培养和 hscTnT 请求和结果可预测更差的结局。