Hainer B L
Department of Family Medicine, East Carolina University School of Medicine, Greenville, North Carolina 27858-4354.
J Fam Pract. 1987 Nov;25(5):497-503.
Cat-scratch disease is a self-limited disease associated with contact with cats that causes regional lymphadenopathy in children and young adults. Recently identification of the probable causative organism, a gram-negative, non-acid-fast coccobacillus, has been achieved through special staining techniques from skin inoculation sites and involved lymph tissue. Differential diagnosis includes a variety of other infectious diseases and neoplasms. Diagnosis of cat-scratch disease can be made by presence of typical clinical findings, history of exposure to cats, results of skin testing to cat-scratch antigen, and in some circumstances, biopsy or fine-needle aspiration from skin inoculation site or involved lymph nodes. Future developments awaiting culture of the suspected bacterium include a vaccine for prevention, rapid diagnostic methods, and antimicrobial testing.
猫抓病是一种与接触猫有关的自限性疾病,可导致儿童和年轻人出现局部淋巴结病。最近,通过特殊染色技术,从皮肤接种部位和受累淋巴组织中已鉴定出可能的致病微生物,即一种革兰氏阴性、非抗酸性的球杆菌。鉴别诊断包括多种其他传染病和肿瘤。猫抓病的诊断可依据典型的临床症状、接触猫的病史、猫抓抗原皮肤试验结果,在某些情况下,还可依据皮肤接种部位或受累淋巴结的活检或细针穿刺结果来做出。有待对疑似细菌进行培养的未来进展包括预防疫苗、快速诊断方法以及抗菌检测。