Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China.
Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, China. Correspondence to: Dr Bing Zhang, Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, No.966 Hengyu Road, Jinan District, Fuzhou, 350000, Fujian, China.
Indian Pediatr. 2023 May 15;60(5):397-403. Epub 2023 Feb 21.
Ingested foreign materials are a common cause for hospital emergency department visit. Foreign objects such as magnets found in the gastrointestinal tract can cause serious problem because magnets attract to each other across the intestinal wall, often resulting in severe damage. We aimed to review the magnitude of the problem, the clinical characteristics and the interventions related to this problem.
A systematic review and meta-analysis of the retrospective studies published in PUBMED, MEDLINE, Web of Science, Embase and Cochrane was conducted. The search was limited to studies published from Jan 1, 2000 to July 31, 2022, with the last search done on August 1, 2022. No publication restrictions or study design filters were applied.
Data from 24 retrospective cohort studies with 2014 patients were included in the review. 63.6% (95% CI 59.9%-67.3%) of children who had swallowed foreign bodies were male, and 43% (95% CI 29.3%-57.3%) children presented with non-specific symptoms or had a complete absence of symptoms. Only 74.7% (95% CI 58.7%-88%) of the children has clear history of ingested foreign bodies. Abdominal surgery was the most prevalent interventions (43.3%, 95%CI 32.5%-54.1%) among the inpatients, while conservative treatments were the second common intervention (40.3%, 95%CI 27.8%-52.9%) among the inpatients and outpatients. Intestinal perforation or fistula occurred in 30.2% (95%CI 22.5%-37.8%) children.
Despite significant heterogeneity among primary studies, our results detail the morbidity, clinical characteristics and interventions associated with ingested magnetic foreign bodies in children.
摄入异物是导致医院急诊就诊的常见原因。胃肠道内发现的磁铁等异物会导致严重问题，因为磁铁会在肠壁两侧相互吸引，通常会导致严重损伤。我们旨在回顾这个问题的严重程度、临床特征以及与该问题相关的干预措施。
对 2000 年 1 月 1 日至 2022 年 7 月 31 日期间在 PUBMED、MEDLINE、Web of Science、Embase 和 Cochrane 发表的回顾性研究进行了系统回顾和荟萃分析。检索仅限于已发表的研究，最后一次检索日期为 2022 年 8 月 1 日。未应用发表限制或研究设计过滤器。
纳入了 24 项回顾性队列研究，共 2014 例患者的数据。吞下异物的患儿中，63.6%（95%可信区间 59.9%-67.3%）为男性，43%（95%可信区间 29.3%-57.3%）的患儿表现为非特异性症状或完全无症状。仅有 74.7%（95%可信区间 58.7%-88%）的患儿有明确的异物摄入史。住院患儿中最常见的干预措施是腹部手术（43.3%，95%可信区间 32.5%-54.1%），而住院和门诊患儿中第二常见的干预措施是保守治疗（40.3%，95%可信区间 27.8%-52.9%）。30.2%（95%可信区间 22.5%-37.8%）的患儿发生肠穿孔或瘘。
尽管主要研究之间存在显著异质性，但我们的研究结果详细说明了儿童摄入磁性异物的发病率、临床特征和干预措施。
