Cojocaru Anca, Orzan Olguța-Anca, Bîrjovanu Carrol, Andreea Nicolae Cătălina, Petrache Diana, Marinescu Elena-Alexandra, Ciurea Marius-Eugen
PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.
Department of Dermatology, Elias Emergency University Hospital, Bucharest, Romania.
Curr Health Sci J. 2022 Jul-Sep;48(3):340-344. doi: 10.12865/CHSJ.48.03.13. Epub 2022 Sep 30.
Basal cell carcinoma (BCC) is the most common skin cancer in the fair-skinned adult population over 50 years of age and the incidence is rising. Generally, BCC has an indolent course, low mortality and a good prognosis due to low rates of metastasis. Giant basal cell carcinoma is a rare reported oncological entity which accounts for 0.5% to 1% of all cases of BCC and has a diameter larger than 5cm. Basosquamous carcinoma is a rare high-risk type of BCC with clinical and histopathological features of both BCC and squamous cell carcinoma. A 61-year-old female presented to our clinic for a giant bleeding tumor located under her left breast. She initially noted the tumor almost 15 years ago. Although the patient was a nurse, she was afraid to seek medical advice until an episode of significant bleeding. At presentation the tumor was a 15/7cm in size, was invading the underlying structures and had a central ulceration. The margins of the tumoral plaque had several nodules and pearly structures suggesting the possible clinical diagnosis of BCC.
基底细胞癌（BCC）是50岁以上白种成年人中最常见的皮肤癌，且发病率正在上升。一般来说，BCC病程进展缓慢，死亡率低，由于转移率低，预后良好。巨大基底细胞癌是一种罕见的肿瘤实体，占所有BCC病例的0.5%至1%，直径大于5厘米。基底鳞状细胞癌是一种罕见的高风险BCC类型，具有BCC和鳞状细胞癌的临床及组织病理学特征。一名61岁女性因左乳房下方出现巨大出血性肿瘤前来我院就诊。她大约在15年前首次发现该肿瘤。尽管患者是一名护士，但直到发生一次大量出血事件，她才敢寻求医疗建议。就诊时，肿瘤大小为15/7厘米，侵犯了深层结构，并有中央溃疡。肿瘤斑块边缘有几个结节和珍珠样结构，提示可能的临床诊断为BCC。
