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精囊梭形细胞/多形性脂肪瘤:一种罕见的良性间叶性肿瘤的首次描述。

Spindle cell/pleomorphic lipoma of the seminal vesicle: First description of a rare benign mesenchymal tumor.

作者信息

Lyatoshinsky Pavel, Pratsinis Manolis, Markert Eva, Schmid Hans-Peter, Müllhaupt Gautier

机构信息

Department of Urology, Institute for Medicine, University St. Gallen, St. Gallen, Switzerland.

Department of Urology, University of California-Davis Medical Center, Sacramento, CA, USA.

出版信息

Urol Case Rep. 2023 Jan 30;47:102337. doi: 10.1016/j.eucr.2023.102337. eCollection 2023 Mar.

DOI:10.1016/j.eucr.2023.102337
PMID:36816611
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9929669/
Abstract

We describe the first case of a spindle cell/pleomorphic lipoma of the seminal vesicle. A 6.2cm large mass originating from the left seminal vesicle was incidentally detected on imaging for peripheral arterial disease. A transrectal ultrasound-guided biopsy was negative for malignancy. We proceeded with a robotic tumor resection due to the size of the mass and sarcomatoid features present on MR imaging. The final pathological work-up revealed a spindle cell/pleomorphic lipoma, immunohistochemical staining was performed with no malignant features detected, in particular no signs of an atypical lipomatous tumor. Ejaculatory function was preserved with reduced volume at 6-weeks follow-up.

摘要

我们报告首例精囊梭形细胞/多形性脂肪瘤病例。一名因外周动脉疾病行影像学检查时偶然发现起源于左侧精囊的一个6.2厘米大的肿块。经直肠超声引导下活检未发现恶性肿瘤。由于肿块大小及磁共振成像显示的肉瘤样特征,我们进行了机器人辅助肿瘤切除术。最终病理检查显示为梭形细胞/多形性脂肪瘤,免疫组化染色未发现恶性特征,尤其未发现非典型脂肪瘤性肿瘤的迹象。6周随访时射精功能得以保留,但其容量有所减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/9553342c1936/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/4019b8bfd220/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/fa47df41d263/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/9553342c1936/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/4019b8bfd220/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/fa47df41d263/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f32/9929669/9553342c1936/gr3.jpg

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本文引用的文献

1
Seminal Vesicle Tumor Microenvironment.精囊肿瘤微环境。
Adv Exp Med Biol. 2020;1296:309-318. doi: 10.1007/978-3-030-59038-3_19.
2
Bladder lipoma: Moroccan case report.膀胱脂肪瘤:摩洛哥病例报告。
Pan Afr Med J. 2020 Dec 29;37:380. doi: 10.11604/pamj.2020.37.380.25672. eCollection 2020.
3
Case report of seminal vesical schwannoma treated with conservative strategy.采用保守策略治疗精囊神经鞘瘤的病例报告。
Medicine (Baltimore). 2020 Sep 18;99(38):e22307. doi: 10.1097/MD.0000000000022307.
4
A Low-Grade Myxoid Liposarcoma Arising in a Deep-Seated Conventional Lipoma.起源于深部传统脂肪瘤的低级别黏液样脂肪肉瘤。
Int J Surg Pathol. 2019 Dec;27(8):919-922. doi: 10.1177/1066896919857147. Epub 2019 Jun 20.
5
Mixed epithelial-stromal tumor (MEST) of seminal vesicle: a proposal for unified nomenclature.精囊混合性上皮-间质肿瘤(MEST):统一命名的建议。
Adv Anat Pathol. 2015 Mar;22(2):113-20. doi: 10.1097/PAP.0000000000000057.