Laval-Jeantet A M, Miravet L, Bergot C, de Vernejoul M C, Kuntz D, Laval-Jeantet M
Laboratoire de Radiologie Expérimentale et Quantitative, Clinique Rhumatologique Viggo Peterson, Unité INSERM U18, Saint-Louis.
J Radiol. 1987 Aug-Sep;68(8-9):495-502.
Quantitative vertebral CT scan imaging is a method developed to provide direct measurements of mineralization of vertebral body spongy tissue, and is presently the most precise procedure for the early detection of spinal osteoporosis. A fracture threshold has been defined below which are found 95% of patients with a crushed vertebra: it is situated at 70% of the value for mineralization normal for the age of patients. Patients with marked reductions in their level of mineralization can be kept under surveillance before the onset of fracture. In patients with vertebral collapses the density is correlated significantly with the number of crush fractures. In addition, measurement of vertebral spongy bone density has allowed the importance of the vertebral lesion to be determined in various osteoporotic disorders, including those with only cortical fractures, and in this way to differentiate them.
定量椎体CT扫描成像技术是一种用于直接测量椎体松质骨矿化程度的方法,目前是早期检测脊柱骨质疏松症最精确的手段。已定义了一个骨折阈值,95%的椎体压缩患者低于此阈值:该阈值位于患者年龄正常矿化值的70%处。矿化水平显著降低的患者在骨折发生前可接受监测。在椎体塌陷的患者中,密度与压缩骨折的数量显著相关。此外,测量椎体松质骨密度有助于确定各种骨质疏松症中椎体病变的重要性,包括仅发生皮质骨折的情况,并以此进行区分。