Shinmura Kazuya, Demura Satoru, Kato Satoshi, Yokogawa Noriaki, Handa Makoto, Annen Ryohei, Kobayashi Motoya, Yamada Yohei, Nagatani Satoshi, Murakami Hideki, Tsuchiya Hiroyuki
Department of Orthopedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Spine Surg Relat Res. 2022 Oct 28;7(1):60-65. doi: 10.22603/ssrr.2022-0111. eCollection 2023 Jan 27.
Long-term spinal stability after total en bloc spondylectomy (TES) is challenging. The aim of this study was to examine whether the new method could reduce the incidence of instrumentation failure (IF).
We retrospectively compared 116 patients with spinal tumors who underwent TES between 2010 and 2019 and were followed up for >1 year. IF, cage subsidence, and complications were evaluated. Propensity score matching between conventional and new method groups was performed for age, sex, body mass index, preoperative radiotherapy, number of resected vertebrae, number of instrumented vertebrae, tumor level, and follow-up period. There were 25 cases each in the conventional and new method groups. The conventional method used a titanium mesh cage for anterior reconstruction and 5.5-mm-diameter titanium alloy rods for posterior fixation. The new method used a more robust cage for anterior reconstruction, bone grafting was performed around the cage, and 6.0-mm-diameter cobalt chromium rods were used for posterior fixation. We compared the incidence of IF and cage subsidence after TES between the conventional and new method groups.
While 5 out of 25 patients (20.0%) in the conventional method group experienced IF, none from the new method group experienced IF. Three-year implant survival rates were 87.3% in the conventional and 100% in the new method groups. The new method group had a significantly higher implant survival rate (p<0.01). Cage subsidence was observed in 11 of 25 (44/0%) patients in the conventional method and 1 of 25 (4.0%; significantly lower, p<0.05) in the new method group.
The new reconstruction method significantly reduced IF incidence in patients with TES.
全椎体整块切除术(TES)后长期脊柱稳定性具有挑战性。本研究的目的是检验新方法是否能降低内固定失败(IF)的发生率。
我们回顾性比较了2010年至2019年间接受TES并随访超过1年的116例脊柱肿瘤患者。评估了内固定失败、椎间融合器下沉及并发症情况。对传统方法组和新方法组进行倾向得分匹配,匹配因素包括年龄、性别、体重指数、术前放疗、切除椎体数量、内固定椎体数量、肿瘤节段及随访时间。传统方法组和新方法组各有25例。传统方法采用钛网椎间融合器进行前路重建,5.5毫米直径的钛合金棒进行后路固定。新方法采用更坚固的椎间融合器进行前路重建,在椎间融合器周围进行植骨,并使用6.0毫米直径的钴铬棒进行后路固定。我们比较了传统方法组和新方法组TES后内固定失败和椎间融合器下沉的发生率。
传统方法组25例患者中有5例(20.0%)发生内固定失败,新方法组无一例发生内固定失败。传统方法组三年植入物生存率为87.3%,新方法组为100%。新方法组植入物生存率显著更高(p<0.01)。传统方法组25例患者中有11例(44.0%)观察到椎间融合器下沉,新方法组25例中有1例(4.0%),显著更低(p<0.05)。
新的重建方法显著降低了TES患者的内固定失败发生率。