Kentucky Spinal Cord Injury Research Center, University of Louisville, Louisville, Kentucky.
Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.
Top Spinal Cord Inj Rehabil. 2023 Winter;29(1):108-117. doi: 10.46292/sci22-00022. Epub 2023 Feb 15.
Urinary tract infections (UTIs) are the most common secondary medical complication following spinal cord injury (SCI), significantly impacting health care resource utilization and costs.
To characterize risk factors and health care utilization costs associated with UTIs in the setting of SCI.
IBM's Marketscan Database from 2000-2019 was utilized to identify individuals with traumatic SCI. Relevant ICD-9 and ICD-10 codes classified individuals into two analysis groups: having ≥ 1 UTI episode or no UTI episodes within 2 years following injury. Demographics (age, sex), insurance type, comorbidities, level of injury (cervical, thoracic, lumbar/sacral), and health care utilization/payments were evaluated.
Of the 6762 individuals retained, 1860 had ≥ 1 UTI with an average of three episodes ( 2). Younger age, female sex, thoracic level of injury, noncommercial insurance, and having at least one comorbidity were associated with increased odds of UTI. Individuals with a UTI in year 1 were 11 times more likely to experience a UTI in year 2. As expected, those with a UTI had a higher rate and associated cost of hospital admission, use of outpatient services, and prescription refills. UTIs were associated with 2.48 times higher cumulated health care resource use payments over 2 years after injury.
In addition to bladder management-related causes, several factors are associated with an increased risk of UTIs following SCI. UTI incidence substantially increases health care utilization costs. An increased understanding of UTI-associated risk factors may improve the ability to identify and manage higher risk individuals with SCI and ultimately optimize their health care utilization.
尿路感染(UTI)是脊髓损伤(SCI)后最常见的继发性医疗并发症,显著影响医疗资源的利用和成本。
描述 SCI 背景下与 UTI 相关的危险因素和医疗保健利用成本。
利用 IBM 的 Marketscan 数据库(2000 年至 2019 年)确定外伤性 SCI 患者。相关的 ICD-9 和 ICD-10 编码将个体分为两组:在损伤后 2 年内有≥1 次 UTI 发作或无 UTI 发作。评估了人口统计学特征(年龄、性别)、保险类型、合并症、损伤水平(颈椎、胸、腰/骶)以及医疗保健的利用/支付情况。
在保留的 6762 名个体中,有 1860 名患有≥1 次 UTI,平均发作 3 次(2)。年龄较小、女性、胸段损伤、非商业保险和至少有一种合并症与 UTI 的发生几率增加相关。在第 1 年患有 UTI 的个体在第 2 年更有可能发生 UTI。正如预期的那样,患有 UTI 的个体住院、使用门诊服务和处方续配的比率和相关费用更高。UTI 导致个体在损伤后 2 年内的累计医疗资源使用支付增加了 2.48 倍。
除了与膀胱管理相关的原因外,还有几个因素与 SCI 后 UTI 的风险增加相关。UTI 的发生率显著增加了医疗保健利用成本。对 UTI 相关危险因素的更多了解可能会提高识别和管理 SCI 高危个体的能力,并最终优化他们的医疗保健利用。