Department of Cardiovascular, Guangzhou University of Chinese Medicine First Affiliated Hospital, Guangzhou, China.
Department of Cardiovascular, Liuzhou Traditional Chinese Medical Hospital, Liuzhou, China.
Medicine (Baltimore). 2023 Feb 10;102(6):e32953. doi: 10.1097/MD.0000000000032953.
The relationship between the Charlson comorbidity index (CCI) and short-term readmission is as yet unknown. Therefore, we aimed to investigate whether the CCI was independently related to short-term readmission in patients with heart failure (HF) after adjusting for other covariates. From December 2016 to June 2019, 2008 patients who underwent HF were enrolled in the study to determine the relationship between CCI and short-term readmission. Patients with HF were divided into 2 categories based on the predefined CCI (low < 3 and high > =3). The relationships between CCI and short-term readmission were analyzed in multivariable logistic regression models and a 2-piece linear regression model. In the high CCI group, the risk of short-term readmission was higher than that in the low CCI group. A curvilinear association was found between CCI and short-term readmission, with a saturation effect predicted at 2.97. In patients with HF who had CCI scores above 2.97, the risk of short-term readmission increased significantly (OR, 2.66; 95% confidence interval, 1.566-4.537). A high CCI was associated with increased short-term readmission in patients with HF, indicating that the CCI could be useful in estimating the readmission rate and has significant predictive value for clinical outcomes in patients with HF.
Charlson 共病指数（CCI）与短期再入院之间的关系尚不清楚。因此，我们旨在研究 CCI 是否在调整其他协变量后与心力衰竭（HF）患者的短期再入院独立相关。从 2016 年 12 月至 2019 年 6 月，共纳入 2008 例接受 HF 治疗的患者，以确定 CCI 与短期再入院之间的关系。根据预设的 CCI（低<3 分和高≥3 分）将 HF 患者分为 2 类。使用多变量逻辑回归模型和两段线性回归模型分析 CCI 与短期再入院之间的关系。在高 CCI 组中，短期再入院的风险高于低 CCI 组。CCI 与短期再入院之间存在曲线关系，预计在 2.97 处出现饱和效应。在 CCI 评分高于 2.97 的 HF 患者中，短期再入院的风险显著增加（OR，2.66；95%置信区间，1.566-4.537）。高 CCI 与 HF 患者短期再入院风险增加相关，表明 CCI 可用于估计再入院率，对 HF 患者的临床结局具有重要预测价值。
