Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou, China.
Department of Orthopaedic Surgery, Dushu Lake Hospital Affiliated to Soochow University, 9 Chongwen Road, Suzhou, China.
J Orthop Surg Res. 2023 Feb 23;18(1):135. doi: 10.1186/s13018-023-03608-9.
To retrospectively compare the safety and efficacy of percutaneous kyphoplasty (PKP), internal fixation (IF), and kyphoplasty combined with internal fixation (KP + IF) in treating metastatic vertebral fracture (MVF) with posterior wall damage.
87 patients with MVF with posterior wall damage underwent surgery. In Group PKP, 36 patients underwent PKP; in Group IF, 20 patients underwent pedicle screw fixation; and in Group KP + IF, 31 patients underwent kyphoplasty combined with pedicle screw fixation. Operative time, intraoperative blood loss, clinical and radiological results, and complication rate in each group were evaluated and compared.
Significant improvement on the VAS, ODI scores, vertebral height and local kyphotic angle (LKA) was noted in each group (P < 0.001). Group PKP and Group KP + IF achieved better pain relief than Group IF (P < 0.05). At postoperative 3 days, Group PKP had better pain relief than Group KP + IF (P < 0.05). At other follow-up time points, there were no differences between Group PKP and KP + IF (P > 0.05). Group KP + IF and Group IF were more efficacious than Group PKP in terms of height restoration and LKA correction (P < 0.05). Group KP + IF had a higher incidence of postoperative complications than Group PKP and Group IF(P < 0.05).
PKP was safe and effective in treating MVF with posterior wall damage. It can achieve similar clinical outcomes compared to KP + IF, but associated with less operative time, less blood loss and fewer complications. IF alone should not be the first treatment option for its poorer analgesic effect.
回顾性比较经皮椎体后凸成形术(PKP)、内固定(IF)和球囊扩张椎体后凸成形术联合内固定(KP+IF)治疗伴后壁损伤的转移瘤性椎体骨折(MVF)的安全性和疗效。
87 例伴后壁损伤的 MVF 患者接受手术治疗。PKP 组 36 例行 PKP,IF 组 20 例行椎弓根螺钉固定,KP+IF 组 31 例行球囊扩张椎体后凸成形术联合椎弓根螺钉固定。评估并比较各组的手术时间、术中出血量、临床和影像学结果及并发症发生率。
各组 VAS、ODI 评分、椎体高度和局部后凸角(LKA)均有显著改善(P<0.001)。PKP 组和 KP+IF 组的止痛效果优于 IF 组(P<0.05)。术后 3d,PKP 组的止痛效果优于 KP+IF 组(P<0.05)。在其他随访时间点,PKP 组和 KP+IF 组之间无差异(P>0.05)。在椎体高度恢复和 LKA 矫正方面,KP+IF 组和 IF 组的疗效优于 PKP 组(P<0.05)。KP+IF 组术后并发症发生率高于 PKP 组和 IF 组(P<0.05)。
PKP 治疗伴后壁损伤的 MVF 安全有效,与 KP+IF 相比,可获得相似的临床效果,但手术时间、出血量更少,并发症更少。IF 单独应用不应作为首选治疗方案,因其止痛效果较差。