Pediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.
Unit of Intensive Care and Neonatology, University Hospital "Rodolico - San Marco", PO "San Marco", Catania, Italy.
Acta Neurol Belg. 2023 Aug;123(4):1339-1344. doi: 10.1007/s13760-023-02211-3. Epub 2023 Feb 24.
Our study aimed to identify a new cut-off for febrile seizure (FS) with a good prognosis, thereby replacing the 15 min described in the standard definition of simple febrile seizure (SFS).
Our study was a retrospective observational study (from January 2018 to December 2018) on children admitted to the Pediatric emergency room of the Santobono-Pausilipon Hospital, Naples, Italy, Pediatric Unit of Latina, Rome, Italy, and Policlinico-Vittorio-Emanuele University Hospital, Catania, Italy, for fever, which developed SFS during the hospitalization. All included patients had their seizures classified as SFS according to the international criteria for epilepsy. We assumed a duration cut-off, and we analyzed the EEG results, neurological follow-up at 12 months, and the recurrence of the febrile seizures the following year. Then, with another calculation, we identify an optimal cut-off of 6 min. Finally, we divided the population into two groups: children with seizures having a duration greater than or less than 6 min.
We found that the population with FS with a duration greater than 6 min presented EEG alteration at follow-up visits, neurological disorders, and a recurrence of FS during the following year.
We suggest to introduce a new cut-off for the duration of FS that better represents the benign nature of a simple febrile event.
本研究旨在确定具有良好预后的热性惊厥（FS）的新截止值，从而取代标准简单热性惊厥（SFS）定义中描述的 15 分钟。
本研究是一项回顾性观察研究（2018 年 1 月至 2018 年 12 月），研究对象为因发热而入住意大利那不勒斯 Santobono-Pausilipon 医院儿科急诊、意大利罗马 Latina 儿科病房和意大利卡塔尼亚 Policlinico-Vittorio-Emanuele 大学医院的儿童。所有纳入的患者均根据国际癫痫标准将其癫痫发作归类为 SFS。我们假设一个持续时间截止值，并分析 EEG 结果、12 个月时的神经随访以及次年的热性惊厥复发情况。然后，通过另一种计算，我们确定了 6 分钟的最佳截止值。最后，我们将人群分为两组：发作持续时间大于或小于 6 分钟的 FS 患儿。
我们发现，持续时间大于 6 分钟的 FS 患儿在随访时存在 EEG 改变、神经障碍以及次年 FS 复发。
我们建议引入新的 FS 持续时间截止值，以更好地反映单纯热性事件的良性性质。
