Ortega-Lozano Ariadna Jazmín, Hernández-Cruz Estefani Yaquelin, Gómez-Sierra Tania, Pedraza-Chaverri José
Department of Biology, Faculty of Chemistry, National Autonomous University of Mexico (UNAM), Mexico City 04510, Mexico.
Postgraduate in Biological Sciences, National Autonomous University of Mexico, University City, Mexico City 04510, Mexico.
Antibiotics (Basel). 2023 Feb 3;12(2):325. doi: 10.3390/antibiotics12020325.
Urinary tract infections (UTIs) are the most common infectious diseases worldwide. These infections are common in all people; however, they are more prevalent in women than in men. The main microorganism that causes 80-90% of UTIs is . However, other bacteria such as , and cause UTIs, and antibiotics are required to treat them. However, UTI treatment can be complicated by antibiotic resistance and biofilm formation. Therefore, medicinal plants, such as spices generally added to foods, can be a therapeutic alternative due to the variety of phytochemicals such as polyphenols, saponins, alkaloids, and terpenes present in their extracts that exert antimicrobial activity. Essential oils extracted from spices have been used to demonstrate their antimicrobial efficacy against strains of pathogens isolated from UTI patients and their synergistic effect with antibiotics. This article summarizes relevant findings on the antimicrobial activity of cinnamon, clove, cumin, oregano, pepper, and rosemary, spices popularly used in Mexico against the uropathogens responsible for UTIs.
尿路感染(UTIs)是全球最常见的传染病。这些感染在所有人中都很常见;然而,女性比男性更普遍。导致80%-90%尿路感染的主要微生物是 。然而,其他细菌如 、 和 也会引起尿路感染,需要使用抗生素进行治疗。然而,尿路感染的治疗可能会因抗生素耐药性和生物膜形成而变得复杂。因此,药用植物,如通常添加到食物中的香料,由于其提取物中存在多种具有抗菌活性的植物化学物质,如多酚、皂苷、生物碱和萜类化合物,可能成为一种治疗选择。从香料中提取的精油已被用于证明其对从尿路感染患者分离出的病原体菌株的抗菌效果以及与抗生素的协同作用。本文总结了墨西哥常用的香料肉桂、丁香、小茴香、牛至、胡椒和迷迭香对导致尿路感染的尿路病原体的抗菌活性的相关研究结果。