Kodina G E, Malysheva A O, Tul'skaia T I, Tarasov N F, Starovoĭtova L P
Med Radiol (Mosk). 1987 Dec;32(12):24-8.
The paper considers an opportunity of using a method of design based on a scheme of a complete factor experiment to find an optimum drug composition, citing by way of example, a process of development of a diagnostic agent for liver scintigraphy on the basis of the calcium-phytate complex labelled with 99mTc taking into account biological behavior of drugs of various composition.
本文考虑了利用基于全因子实验方案的设计方法来寻找最佳药物成分的可能性，并举例说明了基于用99mTc标记的植酸钙复合物开发肝脏闪烁显像诊断剂的过程，同时考虑了不同成分药物的生物学行为。
