Vink R, Knoblach S M, Faden A I
Department of Neurology, University of California, School of Medicine, San Francisco 94121.
Magn Reson Med. 1987 Oct;5(4):390-4. doi: 10.1002/mrm.1910050413.
31P magnetic resonance spectroscopy (MRS) was applied in vivo to study metabolic changes in spinal cord after experimental traumatic injury. Severe trauma, resulting in spastic paraplegia, caused an early and sustained loss of high energy phosphates with profound intracellular acidosis. Early metabolic changes after traumatic spinal injury may predict irreversible tissue damage.