二维超声、二维子宫输卵管超声造影及三维超声诊断纵隔子宫的诊断性能——一项系统评价与Meta分析

Diagnostic Performance of Two-Dimensional Ultrasound, Two-Dimensional Sonohysterography and Three-Dimensional Ultrasound in the Diagnosis of Septate Uterus-A Systematic Review and Meta-Analysis.

作者信息

Alcázar Juan Luis, Carriles Isabel, Cajas María Belén, Costa Susana, Fabra Sofia, Cabrero Maria, Castro Elena, Tomaizeh Aida, Laza María Victoria, Monroy Alba, Martinez Irene, Aguilar Maria Isabel, Hernani Elena, Castellet Cristina, Oliva Agustin, Pascual María Ángela, Guerriero Stefano

机构信息

Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.

Department of Obstetrics and Gynecology, Hospital Universitario de Salamanca, 37007 Salamanca, Spain.

出版信息

Diagnostics (Basel). 2023 Feb 20;13(4):807. doi: 10.3390/diagnostics13040807.

BACKGROUND

The septate uterus is the most common congenital uterine anomaly, and hysteroscopy is the gold standard for diagnosing it. The goal of this meta-analysis is to perform a pooled analysis of the diagnostic performance of two-dimensional transvaginal ultrasonography, two-dimensional transvaginal sonohysterography, three-dimensional transvaginal ultrasound, and three-dimensional transvaginal sonohysterography for the diagnosis of the septate uterus.

METHODS

Studies published between 1990 and 2022 were searched in PubMed, Scopus, and Web of Science. From 897 citations, we selected eighteen studies to include in this meta-analysis.

RESULTS

The mean prevalence of uterine septum in this meta-analysis was 27.8%. Pooled sensitivity and specificity were 83% and 99% for two-dimensional transvaginal ultrasonography (ten studies), 94% and 100% for two-dimensional transvaginal sonohysterography (eight studies), and 98% and 100% for three-dimensional transvaginal ultrasound (seven articles), respectively. The diagnostic accuracy of three-dimensional transvaginal sonohysterography was only described in two studies, and we did not calculate the pooled sensitivity and specificity for this method.

CONCLUSION

Three-dimensional transvaginal ultrasound has the best performance capacity for the diagnosis of the septate uterus.

背景

纵隔子宫是最常见的先天性子宫畸形，宫腔镜检查是诊断该病的金标准。本荟萃分析的目的是对二维经阴道超声、二维经阴道子宫声学造影、三维经阴道超声和三维经阴道子宫声学造影诊断纵隔子宫的诊断性能进行汇总分析。

方法

在PubMed、Scopus和Web of Science中检索1990年至2022年间发表的研究。从897篇文献中，我们选择了18项研究纳入本荟萃分析。

结果

本荟萃分析中子宫纵隔的平均患病率为27.8%。二维经阴道超声（10项研究）的汇总敏感性和特异性分别为83%和99%，二维经阴道子宫声学造影（8项研究）为94%和100%，三维经阴道超声（7篇文章）为98%和100%。三维经阴道子宫声学造影的诊断准确性仅在两项研究中有所描述，我们未计算该方法的汇总敏感性和特异性。