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633纳米波长下组织和体模材料的总衰减系数及散射相函数

Total attenuation coefficients and scattering phase functions of tissues and phantom materials at 633 nm.

作者信息

Flock S T, Wilson B C, Patterson M S

机构信息

Department of Physics, Hamilton Regional Cancer Centre, Ontario, Canada.

出版信息

Med Phys. 1987 Sep-Oct;14(5):835-41. doi: 10.1118/1.596010.

DOI:10.1118/1.596010
PMID:3683313
Abstract

Measurements have been made of the total attenuation coefficient sigma t and the scattering phase function, S(theta), of 632.8 nm of light for a number of animal model tissues, blood, and inert scattering and absorbing media. Polystyrene microspheres of known size and refractive index, for which sigma t and S(theta) can be calculated by Mie theory, were used to test the experimental methods. The purpose of the study was to define typical ranges for these optical properties of tissues, as a contribution to the development of experimental and theoretical methods of light dosimetry in tissue, particularly related to photodynamic therapy of solid tumors. The results demonstrate that, for the representative tissues studied, the total attenuation coefficients are of the order of 10-100 mm-1, and that the scattering is highly forward peaked, with average cosine of scatter in the range 0.6-0.97.

摘要

已对多种动物模型组织、血液以及惰性散射和吸收介质在632.8 nm波长光下的总衰减系数σt和散射相函数S(θ)进行了测量。已知尺寸和折射率的聚苯乙烯微球,其σt和S(θ)可通过米氏理论计算,被用于测试实验方法。本研究的目的是确定组织这些光学特性的典型范围,以助力组织光剂量学实验和理论方法的发展,特别是与实体瘤光动力疗法相关的方法。结果表明,对于所研究的代表性组织,总衰减系数在10 - 100 mm⁻¹量级,且散射高度向前 peaked,散射的平均余弦值在0.6 - 0.97范围内。 (注:原文中“peaked”这个词似乎有误,可能是“peakedness”之类的词才更符合语境,这里按原文翻译了。)

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