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2019冠状病毒病大流行期间乳腺癌的腋窝治疗管理(美国外科医师学会肿瘤学组Z0011标准与术中实时逆转录聚合酶链反应检测的关联)

Axillary Treatment Management in Breast Cancer during COVID-19 Pandemic (Association between ACOSOG Z0011 Criteria and OSNA Test).

作者信息

Anedda Giacomo, Cappellacci Federico, Canu Gian Luigi, Farris Stefania, Calò Pietro Giorgio, Dessena Massimo, Medas Fabio

机构信息

Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.

Polispecialistyc Surgery Unit, Policlinico Universitario "Duilio Casula", 09042 Cagliari, Italy.

出版信息

J Pers Med. 2023 Jan 29;13(2):241. doi: 10.3390/jpm13020241.

DOI:10.3390/jpm13020241
PMID:36836475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9960710/
Abstract

The outbreak of the SARS-COVID-2 pandemic (COVID-19) had a significant effect on the organisation of healthcare systems. Surgical units saw a significant reduction in the volume of surgical procedures performed, with lengthening waiting lists as a consequence. We assessed the surgical activity in relation to breast cancer that took place at the University Hospital of Cagliari, Italy, from February 2018 to March 2022. Two phases were identified based on the epidemiological circumstances: Phase 1-February 2018 to February 2020; Phase 2-March 2020 to March 2022. The surgery performed in the two phases was then compared. All the patients in our sample underwent a breast surgical procedure involving a lymph node biopsy using OSNA associated with the ACOSOG Z0011 criteria. In the study period overall at our facility, there were 4214 procedures, 417 of which involved breast surgery. In Phase 2, 91 procedures were performed using the OSNA method and ACOSOG Z0011 criteria, enabling the intraoperative staging of axillary nodes. Axillary treatment in breast cancer using this approach resulted in a significant reduction in the number of reoperations for the radicalisation of metastatic sentinel lymph nodes.

摘要

严重急性呼吸综合征冠状病毒2大流行(COVID-19)的爆发对医疗系统的组织产生了重大影响。外科科室进行的手术量显著减少,导致等待名单延长。我们评估了2018年2月至2022年3月期间在意大利卡利亚里大学医院进行的与乳腺癌相关的手术活动。根据流行病学情况确定了两个阶段:第1阶段——2018年2月至2020年2月;第2阶段——2020年3月至2022年3月。然后比较了两个阶段进行的手术。我们样本中的所有患者均接受了涉及使用与美国外科医师学会肿瘤学组(ACOSOG)Z0011标准相关的一步核酸分析法(OSNA)进行淋巴结活检的乳腺外科手术。在我们机构的整个研究期间,共进行了4214例手术,其中417例涉及乳腺手术。在第2阶段,使用OSNA方法和ACOSOG Z0011标准进行了91例手术,从而能够在术中对腋窝淋巴结进行分期。采用这种方法进行乳腺癌腋窝治疗,显著减少了转移性前哨淋巴结根治性再手术的次数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/9960710/9e66576896ed/jpm-13-00241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/9960710/9e66576896ed/jpm-13-00241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf2f/9960710/9e66576896ed/jpm-13-00241-g001.jpg

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