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可生物吸收镁合金前交叉韧带干涉螺钉与传统干涉螺钉固定性能的体外研究

In Vitro Investigation of the Fixation Performance of a Bioabsorbable Magnesium ACL Interference Screw Compared to a Conventional Interference Screw.

作者信息

Siroros Nad, Merfort Ricarda, Liu Yu, Praster Maximilian, Hildebrand Frank, Michalik Roman, Eschweiler Jörg

机构信息

Department of Orthopaedics, Trauma, and Reconstructive Surgery, University Hospital RWTH Aachen, 52074 Aachen, Germany.

出版信息

Life (Basel). 2023 Feb 10;13(2):484. doi: 10.3390/life13020484.

Abstract

An anterior cruciate ligament (ACL) reconstruction is a common treatment for patients with ACL rupture that aims to regain pre-injury knee stability and kinematics. During the ACL reconstruction, one method to fix the graft is the use of an interference screw (IS). The IS should provide initial stability and secure the graft during the healing period. In recent years, magnesium has emerged as an alternative material to permanent metal and polymer ISs. In addition, differences in designs, such as the shape of the IS, can influence the fixation performance of the IS. Therefore, in this biomechanical experiment, two different screw designs with two ligament materials were compared in an insertion and a pull-out test at a rate of 1 mm/s. The screw designs were a conventional polymer screw and a magnesium screw. Porcine tendon and nylon rope were used as ligament materials. All tests were performed in polyurethane foam blocks with 15 PCF density (Synbone AG, Switzerland). As a result, both screw designs required an insertion torque of less than 3 Nm. There was a significant difference between the porcine and nylon rope in pull-out tests for each screw design. The magnesium screw had the highest pull-out force at 412.14 ± 50.00 N for porcine tendon and 707.38 ± 21.81 N for nylon rope. There were no significant differences in tunnel widening (narrow-wide ratio) between each ligament material. The magnesium screw showed the lowest narrow-wide tunnel ratio, implying a better ability to compress the graft to the tunnel. In conclusion, a more optimized magnesium IS design resulted in better graft fixation and an improved ACL reconstruction outcome.

摘要

前交叉韧带(ACL)重建是ACL断裂患者的常见治疗方法,旨在恢复伤前膝关节的稳定性和运动学。在ACL重建过程中,固定移植物的一种方法是使用干涉螺钉(IS)。IS应在愈合期提供初始稳定性并固定移植物。近年来,镁已成为永久性金属和聚合物IS的替代材料。此外,设计上的差异,如IS的形状,会影响IS的固定性能。因此,在本生物力学实验中,以1mm/s的速度,在插入和拔出试验中比较了两种不同的螺钉设计与两种韧带材料。螺钉设计为传统聚合物螺钉和镁螺钉。猪腱和尼龙绳用作韧带材料。所有试验均在密度为15PCF的聚氨酯泡沫块(瑞士Synbone AG公司)中进行。结果,两种螺钉设计的插入扭矩均小于3 Nm。每种螺钉设计在拔出试验中,猪腱和尼龙绳之间存在显著差异。镁螺钉的拔出力最高,猪腱的拔出力为412.14±50.00 N,尼龙绳的拔出力为707.38±21.81 N。每种韧带材料在隧道加宽(窄-宽比)方面没有显著差异。镁螺钉的窄-宽隧道比最低,这意味着其将移植物压缩至隧道的能力更强。总之,更优化的镁IS设计可实现更好的移植物固定,并改善ACL重建结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b701/9959181/c68cf2cd4dd1/life-13-00484-g001.jpg

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