Anwar Faheem, Haider Fatima, Khan Sarmir, Ahmad Ibrar, Ahmed Naveed, Imran Muhammad, Rashid Summya, Ren Zhi-Guang, Khattak Saadullah, Ji Xin-Ying
Department of Biotechnology and Genetic Engineering, Hazara University, Mansehra 21300, Pakistan.
Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China.
Life (Basel). 2023 Feb 14;13(2):522. doi: 10.3390/life13020522.
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.
猴痘病毒是一种双链DNA病毒,可导致人类和哺乳动物患病。它是一种人畜共患病毒,属于正痘病毒属,痘病毒科,在许多方面与天花病毒有关。1970年,刚果民主共和国首次报告了人类猴痘病例。2022年4月,非洲、北半球和西半球的广泛地区记录了几例病例。本综述重点介绍了猴痘病毒的分类、感染期间的临床表现以及对人类的致病性。此外,本综述还强调了用于病毒检测的不同诊断方法。