Department of Orthopaedic Surgery, Julius-Maximilians University Wuerzburg, Koenig-Ludwig-Haus, Brettreichstrasse 11, 97074 Wuerzburg, Germany.
Medicina (Kaunas). 2023 Jan 19;59(2):200. doi: 10.3390/medicina59020200.
: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. : We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. : A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. : Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation.
: 目前，全球普通人群中主要截肢的发病率正在下降，而小截肢的发病率正在上升。我们的研究目的是分析这种趋势是否反映在我们骨科大学机构接受下肢截肢治疗的骨科患者中。: 我们进行了一项单中心回顾性研究，纳入了 2007 年 1 月至 2019 年 12 月期间因下肢截肢（LEA）转诊至我院骨科的患者。获取的数据为截肢年份、年龄、性别、截肢水平和截肢原因。采用 t 检验和卡方检验比较男女之间的年龄和截肢率；显著性定义为 < 0.05。线性回归和多变量逻辑回归模型用于检验时间趋势并计算 LEA 的概率。: 共进行了 114 例下肢截肢，其中 60.5%为大截肢。大截肢的数量随着时间的推移而增加，每年增加 0.6 例。男性下肢截肢的比例明显高于女性。男性 LEA 的年龄明显低于女性（男性：54.8 ± 2.8 岁，女性：64.9 ± 3.2 岁， = 0.021）。导致 LEA 的主要原因是肿瘤（28.9%）和与植入物相关的并发症（25.4%）。与植入物相关的并发症和年龄增加了主要截肢的可能性，而畸形、血管疾病和感染更可能导致小截肢。: 在我们的骨科机构中，下肢截肢的病因是多因素的，与其他外科专业不同。近年来，主要截肢的数量持续增加。年龄、性别以及诊断影响着截肢的类型和水平。
