University of Tennessee Health Science Center, Department of Dermatology, Memphis, TN, USA.
University of Tennessee Health Science Center, School of Medicine, Memphis, TN, USA.
Clin Exp Dermatol. 2023 Jun 5;48(6):591-598. doi: 10.1093/ced/llad075.
Pseudofolliculitis barbae (PFB) is a chronic inflammatory condition characterized by follicular and perifollicular papules and pustules primarily affecting the beard and neck area. PFB is a condition that predominantly affects patients with skin of colour. The objective of this paper is to review the epidemiology, pathogenesis and presentation of PFB, and assess the most recent evidence-based treatment options and recommendations for PFB. This is important to increase the quality of care given to target patient populations and to address the prominent disparity in healthcare management of patients with skin of colour. A literature review was conducted utilizing PubMed and Cochrane Library. The key term 'pseudofolliculitis barbae' was used. Search parameters were set to search from 1987 to the present. Results were further narrowed by limiting the literature review to published observational studies, case studies, case series, randomized control trials and case-control studies. Effective treatment for PFB requires a multifaceted approach that targets various aspects of the pathogenesis. Current treatments include preventive measures, antibiotics, corticosteroids, keratolytics, chemical depilatories and/or laser treatments. Topical therapies are currently the mainstay treatment. However, laser hair removal has become a potential long-term treatment option, and additional studies are warranted to understand its long-term efficacy and permanency.
假性须部毛囊炎（PFB）是一种慢性炎症性疾病，其特征为毛囊和毛囊周围丘疹和脓疱，主要影响胡须和颈部区域。PFB 主要影响有色人种的患者。本文旨在回顾 PFB 的流行病学、发病机制和表现，并评估 PFB 的最新循证治疗选择和建议。这对于提高目标患者群体的护理质量以及解决有色人种患者医疗保健管理方面的明显差异非常重要。使用 PubMed 和 Cochrane Library 进行了文献回顾。使用关键词“假性须部毛囊炎”。搜索参数设置为从 1987 年到现在进行搜索。通过将文献综述限制在已发表的观察性研究、病例研究、病例系列、随机对照试验和病例对照研究，进一步缩小了结果范围。治疗 PFB 需要采取多方面的方法，针对发病机制的各个方面。目前的治疗方法包括预防措施、抗生素、皮质类固醇、角质松解剂、化学脱毛剂和/或激光治疗。局部治疗目前是主要的治疗方法。然而，激光脱毛已成为一种潜在的长期治疗选择，需要进一步的研究来了解其长期疗效和永久性。
