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2002年至2016年间英格兰故意一氧化碳中毒住院的时空趋势及风险因素

Spatial and temporal trends and risk factors for intentional carbon monoxide poisoning hospitalizations in England between 2002 and 2016.

作者信息

Roca-Barceló Aina, Crabbe Helen, Close Rebecca, Fahie Helena, Leonardi Giovanni S, Piel Frédéric B

机构信息

Small Area Health Statistics Unit, Medical Research Council (MRC) Centre for Environment and Health, School of Public Health, Imperial College London, London, United Kingdom.

Environmental Epidemiology Group, UK Health Security Agency, Radiation, Chemical and Environmental Hazards Directorate, Chilton, Oxon, United Kingdom; National Institute of Health Research (NIHR) Health Protection Research Unit (HPRU) in Environmental Exposures & Health, Imperial College London, London, United Kingdom.

出版信息

J Affect Disord. 2023 May 15;329:168-175. doi: 10.1016/j.jad.2023.02.036. Epub 2023 Feb 24.

Abstract

INTRODUCTION

Suicide and mental health disorders are a recognized increasing public concern. Most suicide prevention rely on evidence from mortality data, although suicide attempts are a better predictor for completed suicides. Understanding spatio-temporal patterns and demographic profiles of people at risk can improve suicide prevention schemes, including for carbon monoxide (CO) poisoning, a common method for gas-related suicides.

OBJECTIVE

Describe spatio-temporal patterns of intentional CO poisoning hospitalization rates in England between 2002 and 2016, and identify population sub-groups at risk.

METHODS

We used NHS Digital's Hospital Episode Statistics (HES) routinely collected data on hospital admissions for intentional CO poisoning. We estimated age-standardised rates (ASR) by year, gender and residential small-area characteristics, including rural/urban, deprivation and ethnic composition. Temporal trends were assessed through linear regression and joinpoint regression analysis. Regional differences were explored.

RESULTS

On average, we identified 178 hospital admissions for intentional CO poisoning per year. The ASR decreased substantially over the study period, particularly among males (average annual percent change of -7.8 % (95 % CI: -11.0; -4.6)), in comparison to 3.9 % (95%CI, -6.4; -1.4) among females. Most admissions (81 %) occurred in males. White men aged 35-44 years were particularly at risk. The ASR in London (0.08/100,000) was almost six times lower than in the South-West (0.47/100,000).

CONCLUSIONS

This study provides novel insights into attempted suicides by intentional CO poisoning. Further prevention interventions, targeting sub-groups at risk (i.e. white men in their 30s/40s), need to be developed and implemented to reduce the burden of suicides and of CO poisoning.

摘要

引言

自杀和精神健康障碍是日益受到公众关注的问题。大多数自杀预防工作依赖于死亡率数据提供的证据,尽管自杀未遂是预测自杀死亡的更好指标。了解高危人群的时空模式和人口统计学特征可以改进自杀预防方案,包括针对一氧化碳(CO)中毒这一常见的气体相关自杀方式。

目的

描述2002年至2016年英格兰故意一氧化碳中毒住院率的时空模式,并确定高危人群亚组。

方法

我们使用了英国国家医疗服务体系数字化部门的医院事件统计数据(HES),这些数据是关于故意一氧化碳中毒住院情况的常规收集数据。我们按年份、性别和居住小区特征(包括城乡、贫困程度和种族构成)估算年龄标准化率(ASR)。通过线性回归和连接点回归分析评估时间趋势。探讨区域差异。

结果

平均而言,我们每年确定178例故意一氧化碳中毒住院病例。在研究期间,年龄标准化率大幅下降,男性尤其明显(年均变化率为-7.8%(95%置信区间:-11.0;-4.6)),而女性为3.9%(95%置信区间,-6.4;-1.4)。大多数住院病例(81%)发生在男性身上。35至44岁的白人男性风险尤其高。伦敦的年龄标准化率(0.08/10万)几乎比西南部(0.47/10万)低六倍。

结论

本研究为故意一氧化碳中毒自杀未遂提供了新的见解。需要制定并实施针对高危亚组(即30多岁/40多岁的白人男性)的进一步预防干预措施,以减轻自杀和一氧化碳中毒的负担。

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