Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Korea.
Director of abdominal radiology, Korean Teleradiology Reading Center, Seoul, 06125, Korea.
Sci Rep. 2023 Feb 25;13(1):3267. doi: 10.1038/s41598-023-30330-7.
Percutaneous thermal ablation is a minimally invasive treatment for liver, kidney, lung, bone, and thyroid tumors. This treatment also has been used to treat adrenal tumors in patients, but there is no evidence for the efficacy of thermal ablation of adrenal cysts. The present study was performed to analyze the experience of a single center with percutaneous radiofrequency ablation (RFA) of adrenal cysts and to evaluate its efficacy. The present study enrolled all patients who underwent percutaneous RFA for unilateral adrenal cysts from 2019 to 2021. All patients underwent USG-guided percutaneous aspiration of cystic fluid, followed by RFA. A total nine patients with adrenal cysts were included in this study. All of them underwent technically successful percutaneous RFA, with no immediate complication. Follow-up CT 3 months after RFA showed that six of the nine adrenal cysts showed good responses, with reductions in cyst volume ranging from 86.4 to 97.9%. One patient had poor response in the cyst size (volume reduction rate 11.2%). She underwent secondary RFA with resulting that the cyst volume reduced by 91.1%. After a median follow-up period of 17.2 months, eight patients showed no evidence of regrowth. The patient, who showed evidence of regrowth, declined any other treatment and has been under regular surveillance. None of the nine patients developed adrenal insufficiency during the follow-up period. In conclusion, percutaneous RFA is a safe and effective minimally invasive treatment for adrenal cysts, suggesting that percutaneous RFA may be a good alternative option in selected patients.
经皮热消融是一种针对肝脏、肾脏、肺、骨骼和甲状腺肿瘤的微创治疗方法。这种治疗方法也被用于治疗患者的肾上腺肿瘤,但目前尚无证据表明热消融对肾上腺囊肿有效。本研究旨在分析单一中心经皮射频消融(RFA)治疗肾上腺囊肿的经验,并评估其疗效。本研究纳入了 2019 年至 2021 年间所有接受单侧肾上腺囊肿经皮 RFA 治疗的患者。所有患者均接受超声引导下经皮囊肿液抽吸,然后进行 RFA。本研究共纳入 9 例肾上腺囊肿患者。所有患者均成功接受了经皮 RFA 治疗,无即刻并发症。RFA 后 3 个月的 CT 随访显示,9 例肾上腺囊肿中有 6 例反应良好,囊肿体积缩小率为 86.4%至 97.9%。1 例患者囊肿大小反应不佳(体积缩小率为 11.2%)。她接受了二次 RFA,囊肿体积缩小了 91.1%。中位随访 17.2 个月后,8 例患者无复发证据。有复发证据的患者拒绝了其他任何治疗方法,并一直在接受定期监测。在随访期间,9 例患者均未发生肾上腺功能不全。总之,经皮 RFA 是一种安全有效的治疗肾上腺囊肿的微创方法,提示经皮 RFA 可能是一种有选择的患者的良好替代选择。