Croxatto J O, Iribarren G, Ugrin C, Ebner R, Zarate J O, Sampaolesi R
Fundación Oftalmológica Argentina Jorge Malbran, Buenos Aires, Argentina.
Ophthalmology. 1987 Oct;94(10):1281-5. doi: 10.1016/s0161-6420(87)80012-x.
Malignant melanomas of the conjunctiva are extremely rare in children. The authors report an 11-year-old boy who had a nodule at the limbus in a pigmented area since early childhood. The lesion was excised and the diagnosis of atypical compound nevus was made. Five months later, the patient returned with multiple nodules in the bulbar and palpebral conjunctiva. One of the lesions was excised, and the diagnosis was malignant melanoma. He was lost for follow-up for 6 months; then he presented a large pigmented, vascularized mass protruding through the palpebral aperture. Results of systemic workup for metastatic disease were negative, and an exenteration was performed. A few months later, cervical lymphadenopathy developed followed by extensive metastatic disease.
儿童结膜恶性黑色素瘤极为罕见。作者报告了一名11岁男孩,自幼在色素沉着区域的角膜缘有一个结节。该病变被切除,诊断为非典型复合痣。五个月后,患者因球结膜和睑结膜出现多个结节而复诊。切除其中一个病变,诊断为恶性黑色素瘤。他失访了6个月;随后出现一个大的色素沉着、血管化肿块,从睑裂突出。转移性疾病的全身检查结果为阴性,遂行眼眶内容剜除术。几个月后,出现颈部淋巴结病,随后发生广泛的转移性疾病。